Comparison of Biological Properties of Two Medicinal Extracts of the Tehuacan-Cuicatlan Valley
In the Valley of Tehuacan-Cuicatlan, Cyrtocarpa procera and Bursera morelensis are located and are used in traditional medicine. In this research, several biological properties were evaluated. The methanol extracts of C. procera (MeCp) and B. morelensis (MeBm) were obtained by maceration. The antiba...
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| Veröffentlicht in: | Evidence-based complementary and alternative medicine 2018-01, Vol.2018 (2018), p.1-9 |
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| creator | Barbosa-Cabrera, Elizabeth Hernandez-Portilla, Luis B. Flores, Cesar M. Rodriguez-Monroy, Marco A. Martinez-Elizalde, Karla S. Canales-Martinez, Maria Margarita |
| description | In the Valley of Tehuacan-Cuicatlan, Cyrtocarpa procera and Bursera morelensis are located and are used in traditional medicine. In this research, several biological properties were evaluated. The methanol extracts of C. procera (MeCp) and B. morelensis (MeBm) were obtained by maceration. The antibacterial activities of the extracts were evaluated by the Kirby–Baüer disc-diffusion method. The wound healing activity was evaluated by histopathological analysis. Both extracts had a bacteriostatic effect in the Staphylococcus aureus (MeCp MIC = 0.25 mg/mL and MeBm MIC = 1 mg/mL) and the Vibrio cholerae (MeCp MIC = 1 mg/mL and MeBm MIC = 4 mg/mL). Both extracts demonstrated a wound healing efficacy similar to the reference standard (Recoveron). They also showed a high antioxidant capacity (MeCp SC50 = 5.75 μg/mL and MeBm SC50 = 4.27 μg/mL). These results are related to the concentration of phenols (MeCp = 166 and MeBm = 236.6 mg GAe/g) and flavonoids of MeCp = 16 and MeBm = 22 μg Qe/g. Both extracts, acting in a similar way in microorganisms that cause infection thanks to their antioxidant activity, favor the healing of wounds. This is the first study in which the biological properties of these two species are compared. |
| doi_str_mv | 10.1155/2018/4918090 |
| format | Article |
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In this research, several biological properties were evaluated. The methanol extracts of C. procera (MeCp) and B. morelensis (MeBm) were obtained by maceration. The antibacterial activities of the extracts were evaluated by the Kirby–Baüer disc-diffusion method. The wound healing activity was evaluated by histopathological analysis. Both extracts had a bacteriostatic effect in the Staphylococcus aureus (MeCp MIC = 0.25 mg/mL and MeBm MIC = 1 mg/mL) and the Vibrio cholerae (MeCp MIC = 1 mg/mL and MeBm MIC = 4 mg/mL). Both extracts demonstrated a wound healing efficacy similar to the reference standard (Recoveron). They also showed a high antioxidant capacity (MeCp SC50 = 5.75 μg/mL and MeBm SC50 = 4.27 μg/mL). These results are related to the concentration of phenols (MeCp = 166 and MeBm = 236.6 mg GAe/g) and flavonoids of MeCp = 16 and MeBm = 22 μg Qe/g. Both extracts, acting in a similar way in microorganisms that cause infection thanks to their antioxidant activity, favor the healing of wounds. This is the first study in which the biological properties of these two species are compared.</description><identifier>ISSN: 1741-427X</identifier><identifier>EISSN: 1741-4288</identifier><identifier>DOI: 10.1155/2018/4918090</identifier><identifier>PMID: 30538760</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Antimicrobial agents ; Antioxidants ; Bacteria ; Biological properties ; Cholera toxin ; Comparative analysis ; E coli ; Flavonoids ; Folk medicine ; Isoflavones ; Maceration ; Medicine ; Methicillin ; Microorganisms ; Minimum inhibitory concentration ; Oils & fats ; Phenols ; Staphylococcus aureus ; Waterborne diseases ; Wound healing</subject><ispartof>Evidence-based complementary and alternative medicine, 2018-01, Vol.2018 (2018), p.1-9</ispartof><rights>Copyright © 2018 Karla S. Martinez-Elizalde et al.</rights><rights>COPYRIGHT 2018 John Wiley & Sons, Inc.</rights><rights>Copyright © 2018 Karla S. Martinez-Elizalde et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2018 Karla S. Martinez-Elizalde et al. 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c499t-6d67a42fa6bfba2ea94f5050d41b0abb0034329b77696423e947e99fc32489773</citedby><cites>FETCH-LOGICAL-c499t-6d67a42fa6bfba2ea94f5050d41b0abb0034329b77696423e947e99fc32489773</cites><orcidid>0000-0002-1841-1065 ; 0000-0002-4292-0476</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258104/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6258104/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,885,27924,27925,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30538760$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Kuete, Victor</contributor><contributor>Victor Kuete</contributor><creatorcontrib>Barbosa-Cabrera, Elizabeth</creatorcontrib><creatorcontrib>Hernandez-Portilla, Luis B.</creatorcontrib><creatorcontrib>Flores, Cesar M.</creatorcontrib><creatorcontrib>Rodriguez-Monroy, Marco A.</creatorcontrib><creatorcontrib>Martinez-Elizalde, Karla S.</creatorcontrib><creatorcontrib>Canales-Martinez, Maria Margarita</creatorcontrib><title>Comparison of Biological Properties of Two Medicinal Extracts of the Tehuacan-Cuicatlan Valley</title><title>Evidence-based complementary and alternative medicine</title><addtitle>Evid Based Complement Alternat Med</addtitle><description>In the Valley of Tehuacan-Cuicatlan, Cyrtocarpa procera and Bursera morelensis are located and are used in traditional medicine. In this research, several biological properties were evaluated. The methanol extracts of C. procera (MeCp) and B. morelensis (MeBm) were obtained by maceration. The antibacterial activities of the extracts were evaluated by the Kirby–Baüer disc-diffusion method. The wound healing activity was evaluated by histopathological analysis. Both extracts had a bacteriostatic effect in the Staphylococcus aureus (MeCp MIC = 0.25 mg/mL and MeBm MIC = 1 mg/mL) and the Vibrio cholerae (MeCp MIC = 1 mg/mL and MeBm MIC = 4 mg/mL). Both extracts demonstrated a wound healing efficacy similar to the reference standard (Recoveron). They also showed a high antioxidant capacity (MeCp SC50 = 5.75 μg/mL and MeBm SC50 = 4.27 μg/mL). These results are related to the concentration of phenols (MeCp = 166 and MeBm = 236.6 mg GAe/g) and flavonoids of MeCp = 16 and MeBm = 22 μg Qe/g. Both extracts, acting in a similar way in microorganisms that cause infection thanks to their antioxidant activity, favor the healing of wounds. 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Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Evidence-based complementary and alternative medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Barbosa-Cabrera, Elizabeth</au><au>Hernandez-Portilla, Luis B.</au><au>Flores, Cesar M.</au><au>Rodriguez-Monroy, Marco A.</au><au>Martinez-Elizalde, Karla S.</au><au>Canales-Martinez, Maria Margarita</au><au>Kuete, Victor</au><au>Victor Kuete</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparison of Biological Properties of Two Medicinal Extracts of the Tehuacan-Cuicatlan Valley</atitle><jtitle>Evidence-based complementary and alternative medicine</jtitle><addtitle>Evid Based Complement Alternat Med</addtitle><date>2018-01-01</date><risdate>2018</risdate><volume>2018</volume><issue>2018</issue><spage>1</spage><epage>9</epage><pages>1-9</pages><issn>1741-427X</issn><eissn>1741-4288</eissn><abstract>In the Valley of Tehuacan-Cuicatlan, Cyrtocarpa procera and Bursera morelensis are located and are used in traditional medicine. In this research, several biological properties were evaluated. The methanol extracts of C. procera (MeCp) and B. morelensis (MeBm) were obtained by maceration. The antibacterial activities of the extracts were evaluated by the Kirby–Baüer disc-diffusion method. The wound healing activity was evaluated by histopathological analysis. Both extracts had a bacteriostatic effect in the Staphylococcus aureus (MeCp MIC = 0.25 mg/mL and MeBm MIC = 1 mg/mL) and the Vibrio cholerae (MeCp MIC = 1 mg/mL and MeBm MIC = 4 mg/mL). Both extracts demonstrated a wound healing efficacy similar to the reference standard (Recoveron). They also showed a high antioxidant capacity (MeCp SC50 = 5.75 μg/mL and MeBm SC50 = 4.27 μg/mL). These results are related to the concentration of phenols (MeCp = 166 and MeBm = 236.6 mg GAe/g) and flavonoids of MeCp = 16 and MeBm = 22 μg Qe/g. Both extracts, acting in a similar way in microorganisms that cause infection thanks to their antioxidant activity, favor the healing of wounds. This is the first study in which the biological properties of these two species are compared.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>30538760</pmid><doi>10.1155/2018/4918090</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-1841-1065</orcidid><orcidid>https://orcid.org/0000-0002-4292-0476</orcidid><oa>free_for_read</oa></addata></record> |
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| subjects | Antimicrobial agents Antioxidants Bacteria Biological properties Cholera toxin Comparative analysis E coli Flavonoids Folk medicine Isoflavones Maceration Medicine Methicillin Microorganisms Minimum inhibitory concentration Oils & fats Phenols Staphylococcus aureus Waterborne diseases Wound healing |
| title | Comparison of Biological Properties of Two Medicinal Extracts of the Tehuacan-Cuicatlan Valley |
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