Concentration-dependent effects of rapamycin on proliferation, migration and apoptosis of endothelial cells in human venous malformation

Rapamycin has been reported to be immunosuppressive and anti-proliferative towards vascular endothelial and smooth muscle cells. The purpose of the present study was to investigate the effects of rapamycin on the biological behaviors of endothelial cells that have been separated from the deformed ve...

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Veröffentlicht in:	Experimental and therapeutic medicine 2018-12, Vol.16 (6), p.4595-4601
Hauptverfasser:	Si, Yameng, Chu, Hanchen, Zhu, Weiwen, Xiao, Tao, Shen, Xiang, Fu, Yu, Xu, Rongyao, Jiang, Hongbing
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Blood circulation disorders Cell adhesion & migration Cell cycle Cell growth Cell migration Cell proliferation Dosage and administration Drug therapy Endothelium Flow cytometry Rapamycin Signal transduction Studies Veins & arteries
Online-Zugang:	Volltext
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