Anti-inflammatory effects of bone marrow mesenchymal stem cells on mice with Alzheimer's disease

Anti-inflammatory effects of bone marrow mesenchymal stem cells (BMSCs) on mice with Alzheimer's disease (AD) were investigated. Twenty amyloid precursor protein (APP)/presenilin-1 (PS1) double transgenic mice were randomly divided into two groups: the AD control group and the stem cell treatme...

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Veröffentlicht in:	Experimental and therapeutic medicine 2018-12, Vol.16 (6), p.5015-5020
Hauptverfasser:	Wei, Yan, Xie, Zhaohong, Bi, Jianzhong, Zhu, Zhengyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Advertising executives Alzheimer's disease Amyloid beta-protein Anti-inflammatory agents Apoptosis Biological response modifiers Biotechnology Bone marrow Care and treatment Cell culture Cell growth Cytokines Deoxyribonucleic acid Development and progression DNA Enzyme-linked immunosorbent assay Enzymes Flow cytometry Fluorescence Gene expression Genes Genetic aspects Genetic engineering Health aspects Humidity Inflammation Interferon Interleukins Medical research Methods Necrosis Patient outcomes Polymerase chain reaction Proteins Rodents Stem cell transplantation Stem cells Transgenic animals Tumor necrosis factor-TNF Tumors
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