Depletion of plasma membrane–associated phosphoinositides mimics inhibition of TRPM7 channels by cytosolic Mg2+, spermine, and pH

Transient receptor potential cation channel subfamily M member 7 (TRPM7) is an ion channel/protein kinase belonging to the TRP melastatin and eEF2 kinase families. Under physiological conditions, most native TRPM7 channels are inhibited by cytoplasmic Mg2+, protons, and polyamines. Currents through...

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Veröffentlicht in:	The Journal of biological chemistry 2018-11, Vol.293 (47), p.18151-18167
Hauptverfasser:	Zhelay, Tetyana, Wieczerzak, Krystyna B., Beesetty, Pavani, Alter, Gerald M., Matsushita, Masayuki, Kozak, J. Ashot
Format:	Artikel
Sprache:	eng
Schlagworte:	Signal Transduction
Online-Zugang:	Volltext
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