Blueberry Supplementation Influences the Gut Microbiota, Inflammation, and Insulin Resistance in High-Fat-Diet-Fed Rats

Gut microbiota dysbiosis has been linked to obesity-associated chronic inflammation. Microbiota manipulation may therefore affect obesity-related comorbidities. Blueberries are rich in anthocyanins, which have anti-inflammatory properties and may alter the gut microbiota. We hypothesized that bluebe...

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Veröffentlicht in:	The Journal of nutrition 2018-02, Vol.148 (2), p.209-219
Hauptverfasser:	Lee, Sunhye, Keirsey, Katherine I, Kirkland, Rebecca, Grunewald, Zachary I, Fischer, Joan G, de La Serre, Claire B
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose Tissue - drug effects Animals Anthocyanins Anthocyanins - administration & dosage Anti-inflammatory agents Bacteria - classification Berries Blueberries Blueberry Plants Cytokines Diet Diet, High-Fat - adverse effects Dietary Fiber - administration & dosage Dietary Supplements Digestive system DNA, Bacterial - analysis Dysbacteriosis Feeding Fruit - chemistry Fruits Gastrointestinal Microbiome - drug effects Gastrointestinal Microbiome - genetics Gastrointestinal tract Gene expression Gene sequencing Glucose tolerance Glucose Tolerance Test High fat diet Inflammation Inflammation - prevention & control Insulin Insulin receptor substrate 1 Insulin resistance Insulin Resistance - physiology Interleukin 1 Intestine Liver - drug effects Male Mucin Nutrition and Disease Obesity Phosphorylation Plant Extracts - administration & dosage Powder Rats Rats, Wistar Ribonucleic acid RNA Rodents rRNA 16S Sequence Analysis, DNA Serine Substrates Sugar Villus
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