Myocardial hypersensitivity to ischemic injury is not reversed by clonidine or propranolol in a predator-based rat model of posttraumatic stress disorder

•Individuals with posttraumatic stress disorder (PTSD) are at increased risk for cardiovascular disease. We previously reported that a predator-based model of PTSD increases myocardial sensitivity to ischemic injury. Heightened sympathetic signaling has a well-established role in the formation of an...

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Veröffentlicht in:Progress in neuro-psychopharmacology & biological psychiatry 2019-03, Vol.89, p.117-124
Hauptverfasser: Rorabaugh, Boyd R., Bui, Albert D., Seeley, Sarah L., Eisenmann, Eric D., Rose, Robert M., Johnson, Brandon L., Huntley, Madelaine R., Heikkila, Megan E., Zoladz, Phillip R.
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Sprache:eng
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