Integrative pipeline for profiling DNA copy number and inferring tumor phylogeny

Abstract Summary Copy number variation is an important and abundant source of variation in the human genome, which has been associated with a number of diseases, especially cancer. Massively parallel next-generation sequencing allows copy number profiling with fine resolution. Such efforts, however,...

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Veröffentlicht in:	Bioinformatics 2018-06, Vol.34 (12), p.2126-2128
Hauptverfasser:	Urrutia, Eugene, Chen, Hao, Zhou, Zilu, Zhang, Nancy R, Jiang, Yuchao
Format:	Artikel
Sprache:	eng
Schlagworte:	Applications Notes
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