Klotho Ameliorates Medullary Fibrosis and Pressure Natriuresis in Hypertensive Rat Kidneys

Renal expression of klotho is reduced in hypertension. Experiments were performed to examine whether exogenous klotho protein supplementation ameliorates pressure natriuresis in early phase of hypertension, using stroke-prone spontaneously hypertensive rats (sp-SHR). The interactions between klotho...

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Veröffentlicht in:	Hypertension (Dallas, Tex. 1979) Tex. 1979), 2018-11, Vol.72 (5), p.1151-1159
Hauptverfasser:	Takenaka, Tsuneo, Inoue, Tsutomu, Miyazaki, Takashi, Kobori, Hiroyuki, Nishiyama, Akira, Ishii, Naohito, Hayashi, Matsuhiko, Suzuki, Hiromichi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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