Sipjeondaebo-tang Alleviates Oxidative Stress-Mediated Liver Injury through Activation of the CaMKK2-AMPK Signaling Pathway

Sipjeondaebo-tang (SDT) is used frequently as a herbal prescription to treat deficiency syndromes in traditional Korean medicine. We investigated the hepatoprotective effects of SDT against oxidative stress and attempted to clarify the underlying molecular mechanisms. SDT pretreatment reduced arachi...

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Veröffentlicht in:	Evidence-based complementary and alternative medicine 2018-01, Vol.2018 (2018), p.1-13
Hauptverfasser:	Park, Chung A., Kim, Kwang Joong, Cho, Il Je, Ku, Sae-Kwang, Byun, Sung Hui, Lee, Jong Rok, Im, Chae Kwang, Ko, Hae Li, Jung, Eun Hye, Kim, Sung Woo, Park, Sang Mi, Kim, Sang Chan
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Hydroxynonenal Activation Alanine Alanine transaminase AMP AMP-activated protein kinase Apoptosis Arachidonic acid Aspartate aminotransferase Ca2+/calmodulin-dependent protein kinase Calcium ions Calcium-binding protein Calcium-binding proteins Calmodulin Carbon tetrachloride Cytotoxicity Evidence-based medicine Glucose Glutathione Hepatocytes Hydrogen peroxide Hydrogen reduction Inflammation Instrument industry Iron Kinases Liver Mitochondria Molecular modelling Nitrotyrosine Oxidation Oxidative stress Phosphorylation Pretreatment Protein kinases Signal transduction
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