Parenteral Succinate Reduces Systemic ROS Production in Septic Rats, but It Does Not Reduce Creatinine Levels

In sepsis, reactive oxygen species (ROS) production is increased. This process takes place mainly within the electron transport chain. ROS production is part of the pathophysiology of multiple organ failure in sepsis. Succinate yields Dihydroflavine-Adenine Dinucleotide (FADH2), which enters the cha...

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Veröffentlicht in:	Oxidative medicine and cellular longevity 2018-01, Vol.2018 (2018), p.1-6
Hauptverfasser:	Stella, Carlos A., Muryan, Alexis, Canzonieri, Romina, Congost, Christian, Burgos, Isabel, Chapela, Sebastián, Alonso, Manuel
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Critical care Electron transport Immune system Infection Kidneys Medicine Metabolism Mortality Neutrophils Nitrogen dioxide Oxidative stress Physiology Reactive oxygen species Rodents Sepsis Surgery
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