N6-methyldeoxyadenosine directs nucleosome positioning in Tetrahymena DNA

N.sup.6-methyldeoxyadenosine (6mA or m.sup.6dA) was shown more than 40 years ago in simple eukaryotes. Recent studies revealed the presence of 6mA in more prevalent eukaryotes, even in vertebrates. However, functional characterizations have been limited. We use Tetrahymena thermophila as a model org...

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Veröffentlicht in:	Genome Biology 2018-11, Vol.19 (1), p.200-200, Article 200
Hauptverfasser:	Luo, Guan-Zheng, Hao, Ziyang, Luo, Liangzhi, Shen, Mingren, Sparvoli, Daniela, Zheng, Yuqing, Zhang, Zijie, Weng, Xiaocheng, Chen, Kai, Cui, Qiang, Turkewitz, Aaron P, He, Chuan
Format:	Artikel
Sprache:	eng
Schlagworte:	Computer applications Deoxyribonucleic acid DNA DNA methylation DNA replication Enzymes Epigenetics Eukaryotes Gene expression Genetic aspects Genomes Integrated software Methylation Methyltransferase Methyltransferases N6-methyladenosine Nucleosomes Organisms Prokaryotes Tetrahymena Transcription
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