Gene-guided discovery and engineering of branched cyclic peptides in plants

The plant kingdom contains vastly untapped natural product chemistry, which has been traditionally explored through the activity-guided approach. Here, we describe a gene-guided approach to discover and engineer a class of plant ribosomal peptides, the branched cyclic lyciumins. Initially isolated f...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2018-11, Vol.115 (46), p.E10961-E10969
Hauptverfasser:	Kersten, Roland D., Weng, Jing-Ke
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological activity Biological Sciences Engineers Feasibility studies Flowering Genes Genomes Genotype & phenotype Genotypes Glycine Lycium barbarum Natural products Nitrogen Organic chemistry Peptides Physical Sciences Plants (botany) PNAS Plus Precursors Tobacco Transgenic plants Tryptophan
Online-Zugang:	Volltext
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