Clinical management and prevention of dental caries in athletes: A four-year randomized controlled clinical trial
The aims of this four-year randomized controlled clinical trial were to gain insights into management and prevention of dental caries and the effect of stannous fluoride products in athletes. Fifty-four participants were randomized into test and control groups. The test group used special stannous f...
Gespeichert in:
| Veröffentlicht in: | Scientific reports 2018-11, Vol.8 (1), p.16991-10, Article 16991 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 10 |
|---|---|
| container_issue | 1 |
| container_start_page | 16991 |
| container_title | Scientific reports |
| container_volume | 8 |
| creator | Frese, C. Wohlrab, T. Sheng, L. Kieser, M. Krisam, J. Frese, F. Wolff, D. |
| description | The aims of this four-year randomized controlled clinical trial were to gain insights into management and prevention of dental caries and the effect of stannous fluoride products in athletes. Fifty-four participants were randomized into test and control groups. The test group used special stannous fluoride products. The primary endpoint dental caries was assessed by the ICDAS-II-System and analyzed both by a linear mixed model for repeated measures and a generalized linear mixed model. During the observation period an increase in caries-free surfaces from 64.91 ± 6.42 at baseline to 73.22 ± 4.43 was observed. In surfaces with caries superficialis and caries media, a decrease from 13.94 ± 5.70 and 2.96 ± 2.55 surfaces at baseline to 7.89 ± 3.18 and 0.46 ± 0.78 after 2.5 years was noted, respectively. The analysis showed no effect of stannous fluoride products, but a significant difference for the time of examination (p |
| doi_str_mv | 10.1038/s41598-018-34777-x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6242938</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2135638988</sourcerecordid><originalsourceid>FETCH-LOGICAL-c522t-439c3bdbbe067fafbdfa9610c620cf43650486a6adde668f450d077cd2e790d3</originalsourceid><addsrcrecordid>eNp9kU1vFSEUhonR2Kb2D7gwJG7cjPI1zODCpLnxK2nipnvCwOGWhoFbmNu0_nq5TlurC9nwJuc57-HwIvSakveU8PFDFbRXY0fo2HExDEN3-wwdMyL6jnHGnj_RR-i01ivSTs-UoOolOuKtRkdFj9H1JoYUrIl4NslsYYa0YJMc3hW4aTrkhLPHrsnGWFMCVBwSNstlhAXqR3yGfd6X7g5MwaV15jn8BIdtTkvJMR7kw4ilBBNfoRfexAqn9_cJuvjy-WLzrTv_8fX75uy8sz1jSye4snxy0wREDt74yXmjJCVWMmK94LInYpRGGudAytGLnjgyDNYxGBRx_AR9Wm13-2kGZ9sCxUS9K2E25U5nE_TflRQu9TbfaMkEU3xsBu_uDUq-3kNd9ByqhRhNgryvmlHeSz6q8YC-_Qe9al-S2nYrxSSlB4qtlC251gL-8TGU6EOmes1Ut0z170z1bWt683SNx5aHBBvAV6C2UtpC-TP7P7a_AAB1r90</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2135626118</pqid></control><display><type>article</type><title>Clinical management and prevention of dental caries in athletes: A four-year randomized controlled clinical trial</title><source>MEDLINE</source><source>EZB Free E-Journals</source><source>DOAJ Directory of Open Access Journals</source><source>Nature Journals Online</source><source>PubMed Central</source><source>Free Full-Text Journals in Chemistry</source><source>Springer Nature OA Free Journals</source><creator>Frese, C. ; Wohlrab, T. ; Sheng, L. ; Kieser, M. ; Krisam, J. ; Frese, F. ; Wolff, D.</creator><creatorcontrib>Frese, C. ; Wohlrab, T. ; Sheng, L. ; Kieser, M. ; Krisam, J. ; Frese, F. ; Wolff, D.</creatorcontrib><description>The aims of this four-year randomized controlled clinical trial were to gain insights into management and prevention of dental caries and the effect of stannous fluoride products in athletes. Fifty-four participants were randomized into test and control groups. The test group used special stannous fluoride products. The primary endpoint dental caries was assessed by the ICDAS-II-System and analyzed both by a linear mixed model for repeated measures and a generalized linear mixed model. During the observation period an increase in caries-free surfaces from 64.91 ± 6.42 at baseline to 73.22 ± 4.43 was observed. In surfaces with caries superficialis and caries media, a decrease from 13.94 ± 5.70 and 2.96 ± 2.55 surfaces at baseline to 7.89 ± 3.18 and 0.46 ± 0.78 after 2.5 years was noted, respectively. The analysis showed no effect of stannous fluoride products, but a significant difference for the time of examination (p < 0.0001). In addition, it could be shown that at any time of examination, the odds of developing caries media on a new surface was significantly lower than at baseline (up to 25-times). Due to biannual dental examinations, professional tooth cleaning and restorative treatment the number of caries-free surfaces increased and the odds of a new surface to be afflicted with caries media decreased 25-fold.</description><identifier>ISSN: 2045-2322</identifier><identifier>EISSN: 2045-2322</identifier><identifier>DOI: 10.1038/s41598-018-34777-x</identifier><identifier>PMID: 30451891</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>692/700/3032/3127 ; 692/700/3032/3150 ; Adult ; Athletes ; Clinical trials ; Dental Care ; Dental caries ; Dental Caries - prevention & control ; Dental Caries - therapy ; Female ; Fluoridation ; Fluorides ; Free surfaces ; Humanities and Social Sciences ; Humans ; Male ; Middle Aged ; multidisciplinary ; Prevention ; Science ; Science (multidisciplinary) ; Sports ; Stannous fluoride ; Teeth ; Young Adult</subject><ispartof>Scientific reports, 2018-11, Vol.8 (1), p.16991-10, Article 16991</ispartof><rights>The Author(s) 2018</rights><rights>2018. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c522t-439c3bdbbe067fafbdfa9610c620cf43650486a6adde668f450d077cd2e790d3</citedby><cites>FETCH-LOGICAL-c522t-439c3bdbbe067fafbdfa9610c620cf43650486a6adde668f450d077cd2e790d3</cites><orcidid>0000-0001-9875-9290</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242938/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6242938/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,727,780,784,864,885,27924,27925,41120,42189,51576,53791,53793</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30451891$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Frese, C.</creatorcontrib><creatorcontrib>Wohlrab, T.</creatorcontrib><creatorcontrib>Sheng, L.</creatorcontrib><creatorcontrib>Kieser, M.</creatorcontrib><creatorcontrib>Krisam, J.</creatorcontrib><creatorcontrib>Frese, F.</creatorcontrib><creatorcontrib>Wolff, D.</creatorcontrib><title>Clinical management and prevention of dental caries in athletes: A four-year randomized controlled clinical trial</title><title>Scientific reports</title><addtitle>Sci Rep</addtitle><addtitle>Sci Rep</addtitle><description>The aims of this four-year randomized controlled clinical trial were to gain insights into management and prevention of dental caries and the effect of stannous fluoride products in athletes. Fifty-four participants were randomized into test and control groups. The test group used special stannous fluoride products. The primary endpoint dental caries was assessed by the ICDAS-II-System and analyzed both by a linear mixed model for repeated measures and a generalized linear mixed model. During the observation period an increase in caries-free surfaces from 64.91 ± 6.42 at baseline to 73.22 ± 4.43 was observed. In surfaces with caries superficialis and caries media, a decrease from 13.94 ± 5.70 and 2.96 ± 2.55 surfaces at baseline to 7.89 ± 3.18 and 0.46 ± 0.78 after 2.5 years was noted, respectively. The analysis showed no effect of stannous fluoride products, but a significant difference for the time of examination (p < 0.0001). In addition, it could be shown that at any time of examination, the odds of developing caries media on a new surface was significantly lower than at baseline (up to 25-times). Due to biannual dental examinations, professional tooth cleaning and restorative treatment the number of caries-free surfaces increased and the odds of a new surface to be afflicted with caries media decreased 25-fold.</description><subject>692/700/3032/3127</subject><subject>692/700/3032/3150</subject><subject>Adult</subject><subject>Athletes</subject><subject>Clinical trials</subject><subject>Dental Care</subject><subject>Dental caries</subject><subject>Dental Caries - prevention & control</subject><subject>Dental Caries - therapy</subject><subject>Female</subject><subject>Fluoridation</subject><subject>Fluorides</subject><subject>Free surfaces</subject><subject>Humanities and Social Sciences</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>multidisciplinary</subject><subject>Prevention</subject><subject>Science</subject><subject>Science (multidisciplinary)</subject><subject>Sports</subject><subject>Stannous fluoride</subject><subject>Teeth</subject><subject>Young Adult</subject><issn>2045-2322</issn><issn>2045-2322</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>C6C</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNp9kU1vFSEUhonR2Kb2D7gwJG7cjPI1zODCpLnxK2nipnvCwOGWhoFbmNu0_nq5TlurC9nwJuc57-HwIvSakveU8PFDFbRXY0fo2HExDEN3-wwdMyL6jnHGnj_RR-i01ivSTs-UoOolOuKtRkdFj9H1JoYUrIl4NslsYYa0YJMc3hW4aTrkhLPHrsnGWFMCVBwSNstlhAXqR3yGfd6X7g5MwaV15jn8BIdtTkvJMR7kw4ilBBNfoRfexAqn9_cJuvjy-WLzrTv_8fX75uy8sz1jSye4snxy0wREDt74yXmjJCVWMmK94LInYpRGGudAytGLnjgyDNYxGBRx_AR9Wm13-2kGZ9sCxUS9K2E25U5nE_TflRQu9TbfaMkEU3xsBu_uDUq-3kNd9ByqhRhNgryvmlHeSz6q8YC-_Qe9al-S2nYrxSSlB4qtlC251gL-8TGU6EOmes1Ut0z170z1bWt683SNx5aHBBvAV6C2UtpC-TP7P7a_AAB1r90</recordid><startdate>20181119</startdate><enddate>20181119</enddate><creator>Frese, C.</creator><creator>Wohlrab, T.</creator><creator>Sheng, L.</creator><creator>Kieser, M.</creator><creator>Krisam, J.</creator><creator>Frese, F.</creator><creator>Wolff, D.</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>C6C</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0001-9875-9290</orcidid></search><sort><creationdate>20181119</creationdate><title>Clinical management and prevention of dental caries in athletes: A four-year randomized controlled clinical trial</title><author>Frese, C. ; Wohlrab, T. ; Sheng, L. ; Kieser, M. ; Krisam, J. ; Frese, F. ; Wolff, D.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c522t-439c3bdbbe067fafbdfa9610c620cf43650486a6adde668f450d077cd2e790d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>692/700/3032/3127</topic><topic>692/700/3032/3150</topic><topic>Adult</topic><topic>Athletes</topic><topic>Clinical trials</topic><topic>Dental Care</topic><topic>Dental caries</topic><topic>Dental Caries - prevention & control</topic><topic>Dental Caries - therapy</topic><topic>Female</topic><topic>Fluoridation</topic><topic>Fluorides</topic><topic>Free surfaces</topic><topic>Humanities and Social Sciences</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>multidisciplinary</topic><topic>Prevention</topic><topic>Science</topic><topic>Science (multidisciplinary)</topic><topic>Sports</topic><topic>Stannous fluoride</topic><topic>Teeth</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Frese, C.</creatorcontrib><creatorcontrib>Wohlrab, T.</creatorcontrib><creatorcontrib>Sheng, L.</creatorcontrib><creatorcontrib>Kieser, M.</creatorcontrib><creatorcontrib>Krisam, J.</creatorcontrib><creatorcontrib>Frese, F.</creatorcontrib><creatorcontrib>Wolff, D.</creatorcontrib><collection>Springer Nature OA Free Journals</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Science Journals</collection><collection>ProQuest Biological Science Journals</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Scientific reports</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Frese, C.</au><au>Wohlrab, T.</au><au>Sheng, L.</au><au>Kieser, M.</au><au>Krisam, J.</au><au>Frese, F.</au><au>Wolff, D.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical management and prevention of dental caries in athletes: A four-year randomized controlled clinical trial</atitle><jtitle>Scientific reports</jtitle><stitle>Sci Rep</stitle><addtitle>Sci Rep</addtitle><date>2018-11-19</date><risdate>2018</risdate><volume>8</volume><issue>1</issue><spage>16991</spage><epage>10</epage><pages>16991-10</pages><artnum>16991</artnum><issn>2045-2322</issn><eissn>2045-2322</eissn><abstract>The aims of this four-year randomized controlled clinical trial were to gain insights into management and prevention of dental caries and the effect of stannous fluoride products in athletes. Fifty-four participants were randomized into test and control groups. The test group used special stannous fluoride products. The primary endpoint dental caries was assessed by the ICDAS-II-System and analyzed both by a linear mixed model for repeated measures and a generalized linear mixed model. During the observation period an increase in caries-free surfaces from 64.91 ± 6.42 at baseline to 73.22 ± 4.43 was observed. In surfaces with caries superficialis and caries media, a decrease from 13.94 ± 5.70 and 2.96 ± 2.55 surfaces at baseline to 7.89 ± 3.18 and 0.46 ± 0.78 after 2.5 years was noted, respectively. The analysis showed no effect of stannous fluoride products, but a significant difference for the time of examination (p < 0.0001). In addition, it could be shown that at any time of examination, the odds of developing caries media on a new surface was significantly lower than at baseline (up to 25-times). Due to biannual dental examinations, professional tooth cleaning and restorative treatment the number of caries-free surfaces increased and the odds of a new surface to be afflicted with caries media decreased 25-fold.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>30451891</pmid><doi>10.1038/s41598-018-34777-x</doi><tpages>10</tpages><orcidid>https://orcid.org/0000-0001-9875-9290</orcidid><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 2045-2322 |
| ispartof | Scientific reports, 2018-11, Vol.8 (1), p.16991-10, Article 16991 |
| issn | 2045-2322 2045-2322 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6242938 |
| source | MEDLINE; EZB Free E-Journals; DOAJ Directory of Open Access Journals; Nature Journals Online; PubMed Central; Free Full-Text Journals in Chemistry; Springer Nature OA Free Journals |
| subjects | 692/700/3032/3127 692/700/3032/3150 Adult Athletes Clinical trials Dental Care Dental caries Dental Caries - prevention & control Dental Caries - therapy Female Fluoridation Fluorides Free surfaces Humanities and Social Sciences Humans Male Middle Aged multidisciplinary Prevention Science Science (multidisciplinary) Sports Stannous fluoride Teeth Young Adult |
| title | Clinical management and prevention of dental caries in athletes: A four-year randomized controlled clinical trial |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-01T07%3A43%3A13IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20management%20and%20prevention%20of%20dental%20caries%20in%20athletes:%20A%20four-year%20randomized%20controlled%20clinical%20trial&rft.jtitle=Scientific%20reports&rft.au=Frese,%20C.&rft.date=2018-11-19&rft.volume=8&rft.issue=1&rft.spage=16991&rft.epage=10&rft.pages=16991-10&rft.artnum=16991&rft.issn=2045-2322&rft.eissn=2045-2322&rft_id=info:doi/10.1038/s41598-018-34777-x&rft_dat=%3Cproquest_pubme%3E2135638988%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2135626118&rft_id=info:pmid/30451891&rfr_iscdi=true |