Whole-Genome Sequencing in Severe Chronic Obstructive Pulmonary Disease

Genome-wide association studies have identified common variants associated with chronic obstructive pulmonary disease (COPD). Whole-genome sequencing (WGS) offers comprehensive coverage of the entire genome, as compared with genotyping arrays or exome sequencing. We hypothesized that WGS in subjects...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	American journal of respiratory cell and molecular biology 2018-11, Vol.59 (5), p.614-622
Hauptverfasser:	Prokopenko, Dmitry, Sakornsakolpat, Phuwanat, Fier, Heide Loehlein, Qiao, Dandi, Parker, Margaret M, McDonald, Merry-Lynn N, Manichaikul, Ani, Rich, Stephen S, Barr, R Graham, Williams, Christopher J, Brantly, Mark L, Lange, Christoph, Beaty, Terri H, Crapo, James D, Silverman, Edwin K, Cho, Michael H
Format:	Artikel
Sprache:	eng
Schlagworte:	African Americans Age Aged Black or African American - statistics & numerical data Case-Control Studies Chronic obstructive pulmonary disease Cohort Studies Female Genes Genetic Predisposition to Disease Genome-wide association studies Genome-Wide Association Study Genomes Genotyping Humans Lung - metabolism Lung - pathology Lung diseases Male Middle Aged Obstructive lung disease Original Research Polymorphism, Single Nucleotide Principal components analysis Pulmonary Disease, Chronic Obstructive - ethnology Pulmonary Disease, Chronic Obstructive - genetics Respiratory function Severity of Illness Index Smoking Studies White People - statistics & numerical data Whole Genome Sequencing - methods
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!