The Effects of Metformin and Weight Loss on Biomarkers Associated With Breast Cancer Outcomes

This study investigated the effects of metformin and weight loss on biomarkers associated with breast cancer prognosis. Overweight/obese postmenopausal breast cancer survivors (n = 333) were randomly assigned to metformin vs placebo and to a weight loss intervention vs control (ie, usual care). The...

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Veröffentlicht in:	JNCI : Journal of the National Cancer Institute 2018-11, Vol.110 (11), p.1239-1247
Hauptverfasser:	Patterson, Ruth E, Marinac, Catherine R, Sears, Dorothy D, Kerr, Jacqueline, Hartman, Sheri J, Cadmus-Bertram, Lisa, Villaseñor, Adriana, Flatt, Shirley W, Godbole, Suneeta, Li, Hongying, Laughlin, Gail A, Oratowski-Coleman, Jesica, Parker, Barbara A, Natarajan, Loki
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Breast Neoplasms - epidemiology Breast Neoplasms - metabolism Breast Neoplasms - mortality California - epidemiology Female Humans Metformin - administration & dosage Patient Outcome Assessment Prognosis Weight Loss - drug effects
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