Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization

The goal of the present investigation was to clarify and compare the structure of genetic and environmental influences on different types (e.g., physical, verbal) of peer victimization experienced by youth in pre-/early adolescence and mid-/late adolescence. Physical, verbal, social, and property-re...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Behavior genetics 2018-11, Vol.48 (6), p.421-431
Hauptverfasser: Eastman, Meridith L., Verhulst, Brad, Rappaport, Lance M., Dirks, Melanie, Sawyers, Chelsea, Pine, Daniel S., Leibenluft, Ellen, Brotman, Melissa A., Hettema, John M., Roberson-Nay, Roxann
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 431
container_issue 6
container_start_page 421
container_title Behavior genetics
container_volume 48
creator Eastman, Meridith L.
Verhulst, Brad
Rappaport, Lance M.
Dirks, Melanie
Sawyers, Chelsea
Pine, Daniel S.
Leibenluft, Ellen
Brotman, Melissa A.
Hettema, John M.
Roberson-Nay, Roxann
description The goal of the present investigation was to clarify and compare the structure of genetic and environmental influences on different types (e.g., physical, verbal) of peer victimization experienced by youth in pre-/early adolescence and mid-/late adolescence. Physical, verbal, social, and property-related peer victimization experiences were assessed in two twin samples (306 pairs, ages 9–14 and 294 pairs, ages 15–20). Cholesky decompositions of individual differences in victimization were conducted, and independent pathway (IP) and common pathway (CP) twin models were tested in each sample. In the younger sample, a Cholesky decomposition best described the structure of genetic and environmental contributors to peer victimization, with no evidence that common additive genetic or environmental factors influence different types of peer victimization. In the older sample, common environmental factors influenced peer victimization types via a general latent liability for peer victimization (i.e., a CP model). Whereas the pre-/early adolescent sample demonstrated no evidence of a shared genetic and environmental structure for different types of peer victimization, the mid-/late adolescent sample demonstrates the emergence of an environmentally-driven latent liability for peer victimization across peer victimization types.
doi_str_mv 10.1007/s10519-018-9923-1
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6233884</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2111142913</sourcerecordid><originalsourceid>FETCH-LOGICAL-c470t-da1c7b964f76223faa73a6fb99f5122da08f83968f4785e2097bce8504e0fe233</originalsourceid><addsrcrecordid>eNp1kVtrFTEUhYMo9lj9Ab5IwBdfornNJS9COa1VKChafQ2ZzM5pykxyTDKF-uvNcGq9gHnZhP2ttfdmIfSc0deM0u5NZrRhilDWE6W4IOwB2rCmE0Rw1T1EG0opIz2X8gg9yfm6fnkrm8foSFAueQU3KJ3sgHyGyRQY8al3DhIECxn7gMsV4C8lLbYsCXB0-BwCFG-xCSM-Czc-xTBDKGbC2xhK8sNSfAwZl4gvb_fVpGo-AST8zdviZ__DrP2n6JEzU4Znd_UYfX13drl9Ty4-nn_YnlwQKztayGiY7QbVSte1nAtnTCdM6walXMM4Hw3tXS9U2zvZ9Q1wqrrBQt9QCdQBF-IYvT347pdhhtHWTZOZ9D752aRbHY3Xf3eCv9K7eKPbKu57WQ1e3Rmk-H2BXPTss4VpMgHikjVn9Umu2Drr5T_odVxSqOetFBVKcNlWih0om2LOCdz9MozqNVF9SFTXRPWaqGZV8-LPK-4VvyKsAD8AubbCDtLv0f93_QnsR60v</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2110393246</pqid></control><display><type>article</type><title>Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization</title><source>Applied Social Sciences Index &amp; Abstracts (ASSIA)</source><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Eastman, Meridith L. ; Verhulst, Brad ; Rappaport, Lance M. ; Dirks, Melanie ; Sawyers, Chelsea ; Pine, Daniel S. ; Leibenluft, Ellen ; Brotman, Melissa A. ; Hettema, John M. ; Roberson-Nay, Roxann</creator><creatorcontrib>Eastman, Meridith L. ; Verhulst, Brad ; Rappaport, Lance M. ; Dirks, Melanie ; Sawyers, Chelsea ; Pine, Daniel S. ; Leibenluft, Ellen ; Brotman, Melissa A. ; Hettema, John M. ; Roberson-Nay, Roxann</creatorcontrib><description>The goal of the present investigation was to clarify and compare the structure of genetic and environmental influences on different types (e.g., physical, verbal) of peer victimization experienced by youth in pre-/early adolescence and mid-/late adolescence. Physical, verbal, social, and property-related peer victimization experiences were assessed in two twin samples (306 pairs, ages 9–14 and 294 pairs, ages 15–20). Cholesky decompositions of individual differences in victimization were conducted, and independent pathway (IP) and common pathway (CP) twin models were tested in each sample. In the younger sample, a Cholesky decomposition best described the structure of genetic and environmental contributors to peer victimization, with no evidence that common additive genetic or environmental factors influence different types of peer victimization. In the older sample, common environmental factors influenced peer victimization types via a general latent liability for peer victimization (i.e., a CP model). Whereas the pre-/early adolescent sample demonstrated no evidence of a shared genetic and environmental structure for different types of peer victimization, the mid-/late adolescent sample demonstrates the emergence of an environmentally-driven latent liability for peer victimization across peer victimization types.</description><identifier>ISSN: 0001-8244</identifier><identifier>ISSN: 1573-3297</identifier><identifier>EISSN: 1573-3297</identifier><identifier>DOI: 10.1007/s10519-018-9923-1</identifier><identifier>PMID: 30242573</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Adolescent ; Adolescent Behavior ; Adolescents ; Age ; Age differences ; Age Factors ; Aggression ; Behavioral Science and Psychology ; Bullying ; Child ; Child development ; Clinical Psychology ; Crime Victims - psychology ; Environment ; Environmental aspects ; Environmental factors ; Genetics, Behavioral ; Health Psychology ; Humans ; Individual differences ; Influence ; Liability ; Original Research ; Peer Group ; Peer relationships ; Property ; Psychology ; Public Health ; Socialization ; Victimization ; Young Adult</subject><ispartof>Behavior genetics, 2018-11, Vol.48 (6), p.421-431</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2018</rights><rights>Behavior Genetics is a copyright of Springer, (2018). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c470t-da1c7b964f76223faa73a6fb99f5122da08f83968f4785e2097bce8504e0fe233</citedby><cites>FETCH-LOGICAL-c470t-da1c7b964f76223faa73a6fb99f5122da08f83968f4785e2097bce8504e0fe233</cites><orcidid>0000-0002-3385-3259</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10519-018-9923-1$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10519-018-9923-1$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>230,314,776,780,881,12825,27901,27902,30976,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30242573$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Eastman, Meridith L.</creatorcontrib><creatorcontrib>Verhulst, Brad</creatorcontrib><creatorcontrib>Rappaport, Lance M.</creatorcontrib><creatorcontrib>Dirks, Melanie</creatorcontrib><creatorcontrib>Sawyers, Chelsea</creatorcontrib><creatorcontrib>Pine, Daniel S.</creatorcontrib><creatorcontrib>Leibenluft, Ellen</creatorcontrib><creatorcontrib>Brotman, Melissa A.</creatorcontrib><creatorcontrib>Hettema, John M.</creatorcontrib><creatorcontrib>Roberson-Nay, Roxann</creatorcontrib><title>Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization</title><title>Behavior genetics</title><addtitle>Behav Genet</addtitle><addtitle>Behav Genet</addtitle><description>The goal of the present investigation was to clarify and compare the structure of genetic and environmental influences on different types (e.g., physical, verbal) of peer victimization experienced by youth in pre-/early adolescence and mid-/late adolescence. Physical, verbal, social, and property-related peer victimization experiences were assessed in two twin samples (306 pairs, ages 9–14 and 294 pairs, ages 15–20). Cholesky decompositions of individual differences in victimization were conducted, and independent pathway (IP) and common pathway (CP) twin models were tested in each sample. In the younger sample, a Cholesky decomposition best described the structure of genetic and environmental contributors to peer victimization, with no evidence that common additive genetic or environmental factors influence different types of peer victimization. In the older sample, common environmental factors influenced peer victimization types via a general latent liability for peer victimization (i.e., a CP model). Whereas the pre-/early adolescent sample demonstrated no evidence of a shared genetic and environmental structure for different types of peer victimization, the mid-/late adolescent sample demonstrates the emergence of an environmentally-driven latent liability for peer victimization across peer victimization types.</description><subject>Adolescent</subject><subject>Adolescent Behavior</subject><subject>Adolescents</subject><subject>Age</subject><subject>Age differences</subject><subject>Age Factors</subject><subject>Aggression</subject><subject>Behavioral Science and Psychology</subject><subject>Bullying</subject><subject>Child</subject><subject>Child development</subject><subject>Clinical Psychology</subject><subject>Crime Victims - psychology</subject><subject>Environment</subject><subject>Environmental aspects</subject><subject>Environmental factors</subject><subject>Genetics, Behavioral</subject><subject>Health Psychology</subject><subject>Humans</subject><subject>Individual differences</subject><subject>Influence</subject><subject>Liability</subject><subject>Original Research</subject><subject>Peer Group</subject><subject>Peer relationships</subject><subject>Property</subject><subject>Psychology</subject><subject>Public Health</subject><subject>Socialization</subject><subject>Victimization</subject><subject>Young Adult</subject><issn>0001-8244</issn><issn>1573-3297</issn><issn>1573-3297</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><sourceid>8G5</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kVtrFTEUhYMo9lj9Ab5IwBdfornNJS9COa1VKChafQ2ZzM5pykxyTDKF-uvNcGq9gHnZhP2ttfdmIfSc0deM0u5NZrRhilDWE6W4IOwB2rCmE0Rw1T1EG0opIz2X8gg9yfm6fnkrm8foSFAueQU3KJ3sgHyGyRQY8al3DhIECxn7gMsV4C8lLbYsCXB0-BwCFG-xCSM-Czc-xTBDKGbC2xhK8sNSfAwZl4gvb_fVpGo-AST8zdviZ__DrP2n6JEzU4Znd_UYfX13drl9Ty4-nn_YnlwQKztayGiY7QbVSte1nAtnTCdM6walXMM4Hw3tXS9U2zvZ9Q1wqrrBQt9QCdQBF-IYvT347pdhhtHWTZOZ9D752aRbHY3Xf3eCv9K7eKPbKu57WQ1e3Rmk-H2BXPTss4VpMgHikjVn9Umu2Drr5T_odVxSqOetFBVKcNlWih0om2LOCdz9MozqNVF9SFTXRPWaqGZV8-LPK-4VvyKsAD8AubbCDtLv0f93_QnsR60v</recordid><startdate>20181101</startdate><enddate>20181101</enddate><creator>Eastman, Meridith L.</creator><creator>Verhulst, Brad</creator><creator>Rappaport, Lance M.</creator><creator>Dirks, Melanie</creator><creator>Sawyers, Chelsea</creator><creator>Pine, Daniel S.</creator><creator>Leibenluft, Ellen</creator><creator>Brotman, Melissa A.</creator><creator>Hettema, John M.</creator><creator>Roberson-Nay, Roxann</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0-V</scope><scope>3V.</scope><scope>7QG</scope><scope>7QJ</scope><scope>7SS</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88G</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ALSLI</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>HEHIP</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2S</scope><scope>M7P</scope><scope>MBDVC</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-3385-3259</orcidid></search><sort><creationdate>20181101</creationdate><title>Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization</title><author>Eastman, Meridith L. ; Verhulst, Brad ; Rappaport, Lance M. ; Dirks, Melanie ; Sawyers, Chelsea ; Pine, Daniel S. ; Leibenluft, Ellen ; Brotman, Melissa A. ; Hettema, John M. ; Roberson-Nay, Roxann</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c470t-da1c7b964f76223faa73a6fb99f5122da08f83968f4785e2097bce8504e0fe233</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Adolescent Behavior</topic><topic>Adolescents</topic><topic>Age</topic><topic>Age differences</topic><topic>Age Factors</topic><topic>Aggression</topic><topic>Behavioral Science and Psychology</topic><topic>Bullying</topic><topic>Child</topic><topic>Child development</topic><topic>Clinical Psychology</topic><topic>Crime Victims - psychology</topic><topic>Environment</topic><topic>Environmental aspects</topic><topic>Environmental factors</topic><topic>Genetics, Behavioral</topic><topic>Health Psychology</topic><topic>Humans</topic><topic>Individual differences</topic><topic>Influence</topic><topic>Liability</topic><topic>Original Research</topic><topic>Peer Group</topic><topic>Peer relationships</topic><topic>Property</topic><topic>Psychology</topic><topic>Public Health</topic><topic>Socialization</topic><topic>Victimization</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Eastman, Meridith L.</creatorcontrib><creatorcontrib>Verhulst, Brad</creatorcontrib><creatorcontrib>Rappaport, Lance M.</creatorcontrib><creatorcontrib>Dirks, Melanie</creatorcontrib><creatorcontrib>Sawyers, Chelsea</creatorcontrib><creatorcontrib>Pine, Daniel S.</creatorcontrib><creatorcontrib>Leibenluft, Ellen</creatorcontrib><creatorcontrib>Brotman, Melissa A.</creatorcontrib><creatorcontrib>Hettema, John M.</creatorcontrib><creatorcontrib>Roberson-Nay, Roxann</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Social Sciences Premium Collection</collection><collection>ProQuest Central (Corporate)</collection><collection>Animal Behavior Abstracts</collection><collection>Applied Social Sciences Index &amp; Abstracts (ASSIA)</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Psychology Database (Alumni)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>Social Science Premium Collection</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>Sociology Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Sociology Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Behavior genetics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Eastman, Meridith L.</au><au>Verhulst, Brad</au><au>Rappaport, Lance M.</au><au>Dirks, Melanie</au><au>Sawyers, Chelsea</au><au>Pine, Daniel S.</au><au>Leibenluft, Ellen</au><au>Brotman, Melissa A.</au><au>Hettema, John M.</au><au>Roberson-Nay, Roxann</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization</atitle><jtitle>Behavior genetics</jtitle><stitle>Behav Genet</stitle><addtitle>Behav Genet</addtitle><date>2018-11-01</date><risdate>2018</risdate><volume>48</volume><issue>6</issue><spage>421</spage><epage>431</epage><pages>421-431</pages><issn>0001-8244</issn><issn>1573-3297</issn><eissn>1573-3297</eissn><abstract>The goal of the present investigation was to clarify and compare the structure of genetic and environmental influences on different types (e.g., physical, verbal) of peer victimization experienced by youth in pre-/early adolescence and mid-/late adolescence. Physical, verbal, social, and property-related peer victimization experiences were assessed in two twin samples (306 pairs, ages 9–14 and 294 pairs, ages 15–20). Cholesky decompositions of individual differences in victimization were conducted, and independent pathway (IP) and common pathway (CP) twin models were tested in each sample. In the younger sample, a Cholesky decomposition best described the structure of genetic and environmental contributors to peer victimization, with no evidence that common additive genetic or environmental factors influence different types of peer victimization. In the older sample, common environmental factors influenced peer victimization types via a general latent liability for peer victimization (i.e., a CP model). Whereas the pre-/early adolescent sample demonstrated no evidence of a shared genetic and environmental structure for different types of peer victimization, the mid-/late adolescent sample demonstrates the emergence of an environmentally-driven latent liability for peer victimization across peer victimization types.</abstract><cop>New York</cop><pub>Springer US</pub><pmid>30242573</pmid><doi>10.1007/s10519-018-9923-1</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-3385-3259</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0001-8244
ispartof Behavior genetics, 2018-11, Vol.48 (6), p.421-431
issn 0001-8244
1573-3297
1573-3297
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6233884
source Applied Social Sciences Index & Abstracts (ASSIA); MEDLINE; SpringerLink Journals
subjects Adolescent
Adolescent Behavior
Adolescents
Age
Age differences
Age Factors
Aggression
Behavioral Science and Psychology
Bullying
Child
Child development
Clinical Psychology
Crime Victims - psychology
Environment
Environmental aspects
Environmental factors
Genetics, Behavioral
Health Psychology
Humans
Individual differences
Influence
Liability
Original Research
Peer Group
Peer relationships
Property
Psychology
Public Health
Socialization
Victimization
Young Adult
title Age-Related Differences in the Structure of Genetic and Environmental Contributions to Types of Peer Victimization
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-05T14%3A30%3A12IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Age-Related%20Differences%20in%20the%20Structure%20of%20Genetic%20and%20Environmental%20Contributions%20to%20Types%20of%20Peer%20Victimization&rft.jtitle=Behavior%20genetics&rft.au=Eastman,%20Meridith%20L.&rft.date=2018-11-01&rft.volume=48&rft.issue=6&rft.spage=421&rft.epage=431&rft.pages=421-431&rft.issn=0001-8244&rft.eissn=1573-3297&rft_id=info:doi/10.1007/s10519-018-9923-1&rft_dat=%3Cproquest_pubme%3E2111142913%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2110393246&rft_id=info:pmid/30242573&rfr_iscdi=true