Modulation of Vaccine-Induced CD4 T Cell Functional Profiles by Changes in Components of HIV Vaccine Regimens in Humans

To date, six vaccine strategies have been evaluated in clinical trials for their efficacy at inducing protective immune responses against HIV infection. However, only the ALVAC-HIV/AIDSVAX B/E vaccine (RV144 trial) has demonstrated protection, albeit modestly (31%; = 0.03). One potential correlate o...

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Veröffentlicht in:Journal of virology 2018-12, Vol.92 (23)
Hauptverfasser: Pissani, Franco, Schulte, Bianca, Eller, Michael A, Schultz, Bruce T, Ratto-Kim, Silvia, Marovich, Mary, Thongcharoen, Prasert, Sriplienchan, Somchai, Rerks-Ngarm, Supachai, Pitisuttithum, Punnee, Esser, Stefan, Alter, Galit, Robb, Merlin L, Kim, Jerome H, Michael, Nelson L, Streeck, Hendrik
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Sprache:eng
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