2‑Aminoadipic Acid–C(O)–Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics

The design and synthesis of prostate specific membrane antigen (PSMA) ligands derived from 2-aminoadipic acid, a building block that has not previously been used to construct PSMA ligands, are reported. The effects of both the linker length and of an N-substituent of our PSMA ligands were probed, an...

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Veröffentlicht in:ACS medicinal chemistry letters 2018-11, Vol.9 (11), p.1099-1104
Hauptverfasser: Nakajima, Ryo, Nováková, Zora, Tueckmantel, Werner, Motlová, Lucia, Bařinka, Cyril, Kozikowski, Alan P
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Sprache:eng
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