MicroRNA‐mediated regulation of T helper type 17/regulatory T‐cell balance in autoimmune disease

Summary T helper type 17 (Th17) cells and regulatory T (Treg) cells are two distinct T‐cell subsets with opposite effects on immune functions. While Th17 cells are a key effector in the immune response and play critical roles in the development of autoimmunity and inflammation, Treg cells orchestrat...

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Veröffentlicht in:	Immunology 2018-12, Vol.155 (4), p.427-434
Hauptverfasser:	Liu, Cuilian, Yang, Haoran, Shi, Weiyun, Wang, Ting, Ruan, Qingguo
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals autoimmune disease Autoimmune diseases Autoimmune Diseases - immunology Autoimmune Diseases - pathology Autoimmunity - immunology Effector cells Experimental allergic encephalomyelitis Gene expression Helper cells Humans immune regulation Immune response Immune system Immunological tolerance Lymphocyte Count Lymphocytes Lymphocytes T Mice microRNAs MicroRNAs - metabolism miRNA Multiple sclerosis Pathogenesis Review Ribonucleic acid RNA T helper type 17/regulatory T balance T-Lymphocytes, Regulatory - immunology Th17 Cells - immunology Transcription
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