Direct Dripping: A High-Temperature, High-Formaldehyde Emission Electronic Cigarette Use Method
Electronic cigarettes (ECIGs) electrically heat and vaporize a liquid solution to produce an inhalable nicotine-containing aerosol. Normally the electrical heater is fed the liquid via an automatic wick system. Some ECIG users, however, elect to directly drip liquid onto an exposed heater coil, repo...
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Veröffentlicht in: | Nicotine & tobacco research 2016-04, Vol.18 (4), p.453-459 |
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creator | Talih, Soha Balhas, Zainab Salman, Rola Karaoghlanian, Nareg Shihadeh, Alan |
description | Electronic cigarettes (ECIGs) electrically heat and vaporize a liquid solution to produce an inhalable nicotine-containing aerosol. Normally the electrical heater is fed the liquid via an automatic wick system. Some ECIG users, however, elect to directly drip liquid onto an exposed heater coil, reportedly for greater vapor production and throat hit. Use of such "direct drip atomizers" (DDAs) may involve greater exposure to non-nicotine toxicants due to the potentially higher temperatures reached by the coil. In this study we examined nicotine and volatile aldehyde (VA) emissions from one type of DDA under various use scenarios, and measured heater temperature.
Aerosols were machine-generated from an NHALER 510 Atomizer powered by an eGo-T battery (Joyetech), using a common PG-based liquid and a fixed puffing regimen. Inter-drip interval, the number of puffs drawn between replenishing the liquid on the coil, was varied from 2-4 puffs/drip. Total particulate matter, nicotine, and VA yields were quantified. Heater temperature was monitored using an infrared camera.
Depending on the condition, VA emissions, including formaldehyde, greatly exceeded values previously reported for conventional ECIGs and combustible cigarettes, both per puff and per unit of nicotine yield. Increasing the inter-drip interval resulted in greater VA emissions, and lower total particulate matter and nicotine yields. Maximum heater coil temperature ranged from 130°C to more than 350°C.
Due to the higher temperatures attained, DDAs are inherently likely to produce high toxicant emissions. The diversity of ECIG use methods, including potential off-label methods, should be considered as ECIG regulatory efforts proceed. |
doi_str_mv | 10.1093/ntr/ntv080 |
format | Article |
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Aerosols were machine-generated from an NHALER 510 Atomizer powered by an eGo-T battery (Joyetech), using a common PG-based liquid and a fixed puffing regimen. Inter-drip interval, the number of puffs drawn between replenishing the liquid on the coil, was varied from 2-4 puffs/drip. Total particulate matter, nicotine, and VA yields were quantified. Heater temperature was monitored using an infrared camera.
Depending on the condition, VA emissions, including formaldehyde, greatly exceeded values previously reported for conventional ECIGs and combustible cigarettes, both per puff and per unit of nicotine yield. Increasing the inter-drip interval resulted in greater VA emissions, and lower total particulate matter and nicotine yields. Maximum heater coil temperature ranged from 130°C to more than 350°C.
Due to the higher temperatures attained, DDAs are inherently likely to produce high toxicant emissions. The diversity of ECIG use methods, including potential off-label methods, should be considered as ECIG regulatory efforts proceed.</description><identifier>ISSN: 1462-2203</identifier><identifier>EISSN: 1469-994X</identifier><identifier>DOI: 10.1093/ntr/ntv080</identifier><identifier>PMID: 25863521</identifier><language>eng</language><publisher>England: Oxford University Press</publisher><subject>Aerosols - administration & dosage ; Aerosols - adverse effects ; Drug Delivery Systems - methods ; Electronic Nicotine Delivery Systems - adverse effects ; Electronic Nicotine Delivery Systems - methods ; Formaldehyde - administration & dosage ; Formaldehyde - adverse effects ; Hazardous Substances - administration & dosage ; Hazardous Substances - adverse effects ; Hot Temperature - adverse effects ; Nebulizers and Vaporizers ; Nicotine - administration & dosage ; Nicotine - adverse effects ; Original Investigation ; Original Investigations ; Particulate Matter - administration & dosage ; Particulate Matter - adverse effects ; Smoking - adverse effects ; Temperature</subject><ispartof>Nicotine & tobacco research, 2016-04, Vol.18 (4), p.453-459</ispartof><rights>The Author 2015</rights><rights>The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.</rights><rights>The Author 2015. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com. 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c400t-dc8db69d8a4e2d773e7d2d057910a3d371ff7582d6ddf15c951bb3939da0c7503</citedby><cites>FETCH-LOGICAL-c400t-dc8db69d8a4e2d773e7d2d057910a3d371ff7582d6ddf15c951bb3939da0c7503</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.jstor.org/stable/pdf/26769338$$EPDF$$P50$$Gjstor$$H</linktopdf><linktohtml>$$Uhttps://www.jstor.org/stable/26769338$$EHTML$$P50$$Gjstor$$H</linktohtml><link.rule.ids>230,315,782,786,805,887,27931,27932,58024,58257</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25863521$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Talih, Soha</creatorcontrib><creatorcontrib>Balhas, Zainab</creatorcontrib><creatorcontrib>Salman, Rola</creatorcontrib><creatorcontrib>Karaoghlanian, Nareg</creatorcontrib><creatorcontrib>Shihadeh, Alan</creatorcontrib><title>Direct Dripping: A High-Temperature, High-Formaldehyde Emission Electronic Cigarette Use Method</title><title>Nicotine & tobacco research</title><addtitle>Nicotine Tob Res</addtitle><description>Electronic cigarettes (ECIGs) electrically heat and vaporize a liquid solution to produce an inhalable nicotine-containing aerosol. Normally the electrical heater is fed the liquid via an automatic wick system. Some ECIG users, however, elect to directly drip liquid onto an exposed heater coil, reportedly for greater vapor production and throat hit. Use of such "direct drip atomizers" (DDAs) may involve greater exposure to non-nicotine toxicants due to the potentially higher temperatures reached by the coil. In this study we examined nicotine and volatile aldehyde (VA) emissions from one type of DDA under various use scenarios, and measured heater temperature.
Aerosols were machine-generated from an NHALER 510 Atomizer powered by an eGo-T battery (Joyetech), using a common PG-based liquid and a fixed puffing regimen. Inter-drip interval, the number of puffs drawn between replenishing the liquid on the coil, was varied from 2-4 puffs/drip. Total particulate matter, nicotine, and VA yields were quantified. Heater temperature was monitored using an infrared camera.
Depending on the condition, VA emissions, including formaldehyde, greatly exceeded values previously reported for conventional ECIGs and combustible cigarettes, both per puff and per unit of nicotine yield. Increasing the inter-drip interval resulted in greater VA emissions, and lower total particulate matter and nicotine yields. Maximum heater coil temperature ranged from 130°C to more than 350°C.
Due to the higher temperatures attained, DDAs are inherently likely to produce high toxicant emissions. The diversity of ECIG use methods, including potential off-label methods, should be considered as ECIG regulatory efforts proceed.</description><subject>Aerosols - administration & dosage</subject><subject>Aerosols - adverse effects</subject><subject>Drug Delivery Systems - methods</subject><subject>Electronic Nicotine Delivery Systems - adverse effects</subject><subject>Electronic Nicotine Delivery Systems - methods</subject><subject>Formaldehyde - administration & dosage</subject><subject>Formaldehyde - adverse effects</subject><subject>Hazardous Substances - administration & dosage</subject><subject>Hazardous Substances - adverse effects</subject><subject>Hot Temperature - adverse effects</subject><subject>Nebulizers and Vaporizers</subject><subject>Nicotine - administration & dosage</subject><subject>Nicotine - adverse effects</subject><subject>Original Investigation</subject><subject>Original Investigations</subject><subject>Particulate Matter - administration & dosage</subject><subject>Particulate Matter - adverse effects</subject><subject>Smoking - adverse effects</subject><subject>Temperature</subject><issn>1462-2203</issn><issn>1469-994X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpVUEtLAzEQDqLYWkXwrngWVieZzesilNYXFLwoeAvZJFu3tN0luxb890ZXqx6GGfgew_cRckLhkoLGq3UX02xAwQ4Z0lzoTOv8ZffrZhljgANy0LYLAEapovtkwLgSyBkdkuNpFYPrzqexappqPT8ke6VdtuHoe4_I8-3N0-Q-mz3ePUzGs8zlAF3mnfKF0F7ZPDAvJQbpmQcuNQWLHiUtS8kV88L7knKnOS0K1Ki9BSc54Ihc977NW7EK3oUUwi5NE6uVje-mtpX5j6yrVzOvN0akPAoxGVz0Bi7WbRtDudVSMJ-1mKQzfS2JfPb325b600MinPaERdvV8RcXUmhEhR8WvWhw</recordid><startdate>20160401</startdate><enddate>20160401</enddate><creator>Talih, Soha</creator><creator>Balhas, Zainab</creator><creator>Salman, Rola</creator><creator>Karaoghlanian, Nareg</creator><creator>Shihadeh, Alan</creator><general>Oxford University Press</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>5PM</scope></search><sort><creationdate>20160401</creationdate><title>Direct Dripping</title><author>Talih, Soha ; Balhas, Zainab ; Salman, Rola ; Karaoghlanian, Nareg ; Shihadeh, Alan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c400t-dc8db69d8a4e2d773e7d2d057910a3d371ff7582d6ddf15c951bb3939da0c7503</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Aerosols - administration & dosage</topic><topic>Aerosols - adverse effects</topic><topic>Drug Delivery Systems - methods</topic><topic>Electronic Nicotine Delivery Systems - adverse effects</topic><topic>Electronic Nicotine Delivery Systems - methods</topic><topic>Formaldehyde - administration & dosage</topic><topic>Formaldehyde - adverse effects</topic><topic>Hazardous Substances - administration & dosage</topic><topic>Hazardous Substances - adverse effects</topic><topic>Hot Temperature - adverse effects</topic><topic>Nebulizers and Vaporizers</topic><topic>Nicotine - administration & dosage</topic><topic>Nicotine - adverse effects</topic><topic>Original Investigation</topic><topic>Original Investigations</topic><topic>Particulate Matter - administration & dosage</topic><topic>Particulate Matter - adverse effects</topic><topic>Smoking - adverse effects</topic><topic>Temperature</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Talih, Soha</creatorcontrib><creatorcontrib>Balhas, Zainab</creatorcontrib><creatorcontrib>Salman, Rola</creatorcontrib><creatorcontrib>Karaoghlanian, Nareg</creatorcontrib><creatorcontrib>Shihadeh, Alan</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Nicotine & tobacco research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Talih, Soha</au><au>Balhas, Zainab</au><au>Salman, Rola</au><au>Karaoghlanian, Nareg</au><au>Shihadeh, Alan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Direct Dripping: A High-Temperature, High-Formaldehyde Emission Electronic Cigarette Use Method</atitle><jtitle>Nicotine & tobacco research</jtitle><addtitle>Nicotine Tob Res</addtitle><date>2016-04-01</date><risdate>2016</risdate><volume>18</volume><issue>4</issue><spage>453</spage><epage>459</epage><pages>453-459</pages><issn>1462-2203</issn><eissn>1469-994X</eissn><abstract>Electronic cigarettes (ECIGs) electrically heat and vaporize a liquid solution to produce an inhalable nicotine-containing aerosol. Normally the electrical heater is fed the liquid via an automatic wick system. Some ECIG users, however, elect to directly drip liquid onto an exposed heater coil, reportedly for greater vapor production and throat hit. Use of such "direct drip atomizers" (DDAs) may involve greater exposure to non-nicotine toxicants due to the potentially higher temperatures reached by the coil. In this study we examined nicotine and volatile aldehyde (VA) emissions from one type of DDA under various use scenarios, and measured heater temperature.
Aerosols were machine-generated from an NHALER 510 Atomizer powered by an eGo-T battery (Joyetech), using a common PG-based liquid and a fixed puffing regimen. Inter-drip interval, the number of puffs drawn between replenishing the liquid on the coil, was varied from 2-4 puffs/drip. Total particulate matter, nicotine, and VA yields were quantified. Heater temperature was monitored using an infrared camera.
Depending on the condition, VA emissions, including formaldehyde, greatly exceeded values previously reported for conventional ECIGs and combustible cigarettes, both per puff and per unit of nicotine yield. Increasing the inter-drip interval resulted in greater VA emissions, and lower total particulate matter and nicotine yields. Maximum heater coil temperature ranged from 130°C to more than 350°C.
Due to the higher temperatures attained, DDAs are inherently likely to produce high toxicant emissions. The diversity of ECIG use methods, including potential off-label methods, should be considered as ECIG regulatory efforts proceed.</abstract><cop>England</cop><pub>Oxford University Press</pub><pmid>25863521</pmid><doi>10.1093/ntr/ntv080</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Oxford University Press Journals All Titles (1996-Current); Alma/SFX Local Collection; JSTOR |
subjects | Aerosols - administration & dosage Aerosols - adverse effects Drug Delivery Systems - methods Electronic Nicotine Delivery Systems - adverse effects Electronic Nicotine Delivery Systems - methods Formaldehyde - administration & dosage Formaldehyde - adverse effects Hazardous Substances - administration & dosage Hazardous Substances - adverse effects Hot Temperature - adverse effects Nebulizers and Vaporizers Nicotine - administration & dosage Nicotine - adverse effects Original Investigation Original Investigations Particulate Matter - administration & dosage Particulate Matter - adverse effects Smoking - adverse effects Temperature |
title | Direct Dripping: A High-Temperature, High-Formaldehyde Emission Electronic Cigarette Use Method |
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