Fully Automated Delineation of Gross Tumor Volume for Head and Neck Cancer on PET-CT Using Deep Learning: A Dual-Center Study

Purpose. In this study, we proposed an automated deep learning (DL) method for head and neck cancer (HNC) gross tumor volume (GTV) contouring on positron emission tomography-computed tomography (PET-CT) images. Materials and Methods. PET-CT images were collected from 22 newly diagnosed HNC patients,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Contrast media and molecular imaging 2018-01, Vol.2018 (2018), p.1-12
Hauptverfasser: Li, Qiaoliang, Huang, Bingsheng, Wang, Tian-Fu, Zheng, Liyun, Wong, Ching-Yee Oliver, Feng, Shi-Ting, Ye, Yufeng, Wu, Po-Man, Chen, Zhewei, Huang, Bin, Liu, Yong
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 12
container_issue 2018
container_start_page 1
container_title Contrast media and molecular imaging
container_volume 2018
creator Li, Qiaoliang
Huang, Bingsheng
Wang, Tian-Fu
Zheng, Liyun
Wong, Ching-Yee Oliver
Feng, Shi-Ting
Ye, Yufeng
Wu, Po-Man
Chen, Zhewei
Huang, Bin
Liu, Yong
description Purpose. In this study, we proposed an automated deep learning (DL) method for head and neck cancer (HNC) gross tumor volume (GTV) contouring on positron emission tomography-computed tomography (PET-CT) images. Materials and Methods. PET-CT images were collected from 22 newly diagnosed HNC patients, of whom 17 (Database 1) and 5 (Database 2) were from two centers, respectively. An oncologist and a radiologist decided the gold standard of GTV manually by consensus. We developed a deep convolutional neural network (DCNN) and trained the network based on the two-dimensional PET-CT images and the gold standard of GTV in the training dataset. We did two experiments: Experiment 1, with Database 1 only, and Experiment 2, with both Databases 1 and 2. In both Experiment 1 and Experiment 2, we evaluated the proposed method using a leave-one-out cross-validation strategy. We compared the median results in Experiment 2 (GTVa) with the performance of other methods in the literature and with the gold standard (GTVm). Results. A tumor segmentation task for a patient on coregistered PET-CT images took less than one minute. The dice similarity coefficient (DSC) of the proposed method in Experiment 1 and Experiment 2 was 0.481∼0.872 and 0.482∼0.868, respectively. The DSC of GTVa was better than that in previous studies. A high correlation was found between GTVa and GTVm (R = 0.99, P
doi_str_mv 10.1155/2018/8923028
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6220410</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2190115369</sourcerecordid><originalsourceid>FETCH-LOGICAL-c537t-ced95addd6ffbc4f99de1fb5081cae21a31f3dacbcbf803d738875f86ac0822d3</originalsourceid><addsrcrecordid>eNqNkctv1DAQhyMEoqVw44wscUGCUD_ycDggrdIX0gqQ2HK1Jva4TUnsxYlBe-B_x6tdlseJk8f2559m_GXZU0ZfM1aWp5wyeSobLiiX97LjdFTmhWD1_UNNm6Ps0TTdUVoUohEPsyNBi1pURXGc_biIw7Ahizj7EWY05AyH3iHMvXfEW3IZ_DSRVRx9IJ_9EEckNpVXCIaAM-Q96i-kBacxkPTi4_kqb1fkeurdTYrCNVkiBJd2b8iCnEUY8hbdnOBPczSbx9kDC8OET_brSXZ9cb5qr_Llh8t37WKZ61LUc67RNCUYYyprO13YpjHIbFdSyTQgZyCYFQZ0pzsrqTC1kLIuraxAU8m5ESfZ213uOnYjGp1aCDCodehHCBvloVd_37j-Vt34b6rinBaMpoAX-4Dgv0acZjX2k8ZhAIc-ToozIWlRCS4T-vwf9M7H4NJ4iWpociaqJlGvdpTefnBAe2iGUbX1qrZe1d5rwp_9OcAB_iUyAS93wG3vDHzv_zMOE4MWftNMsIo24icVw7Th</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2190115369</pqid></control><display><type>article</type><title>Fully Automated Delineation of Gross Tumor Volume for Head and Neck Cancer on PET-CT Using Deep Learning: A Dual-Center Study</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>PubMed Central Open Access</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><creator>Li, Qiaoliang ; Huang, Bingsheng ; Wang, Tian-Fu ; Zheng, Liyun ; Wong, Ching-Yee Oliver ; Feng, Shi-Ting ; Ye, Yufeng ; Wu, Po-Man ; Chen, Zhewei ; Huang, Bin ; Liu, Yong</creator><contributor>Pascali, Giancarlo ; Giancarlo Pascali</contributor><creatorcontrib>Li, Qiaoliang ; Huang, Bingsheng ; Wang, Tian-Fu ; Zheng, Liyun ; Wong, Ching-Yee Oliver ; Feng, Shi-Ting ; Ye, Yufeng ; Wu, Po-Man ; Chen, Zhewei ; Huang, Bin ; Liu, Yong ; Pascali, Giancarlo ; Giancarlo Pascali</creatorcontrib><description>Purpose. In this study, we proposed an automated deep learning (DL) method for head and neck cancer (HNC) gross tumor volume (GTV) contouring on positron emission tomography-computed tomography (PET-CT) images. Materials and Methods. PET-CT images were collected from 22 newly diagnosed HNC patients, of whom 17 (Database 1) and 5 (Database 2) were from two centers, respectively. An oncologist and a radiologist decided the gold standard of GTV manually by consensus. We developed a deep convolutional neural network (DCNN) and trained the network based on the two-dimensional PET-CT images and the gold standard of GTV in the training dataset. We did two experiments: Experiment 1, with Database 1 only, and Experiment 2, with both Databases 1 and 2. In both Experiment 1 and Experiment 2, we evaluated the proposed method using a leave-one-out cross-validation strategy. We compared the median results in Experiment 2 (GTVa) with the performance of other methods in the literature and with the gold standard (GTVm). Results. A tumor segmentation task for a patient on coregistered PET-CT images took less than one minute. The dice similarity coefficient (DSC) of the proposed method in Experiment 1 and Experiment 2 was 0.481∼0.872 and 0.482∼0.868, respectively. The DSC of GTVa was better than that in previous studies. A high correlation was found between GTVa and GTVm (R = 0.99, P&lt;0.001). The median volume difference (%) between GTVm and GTVa was 10.9%. The median values of DSC, sensitivity, and precision of GTVa were 0.785, 0.764, and 0.789, respectively. Conclusion. A fully automatic GTV contouring method for HNC based on DCNN and PET-CT from dual centers has been successfully proposed with high accuracy and efficiency. Our proposed method is of help to the clinicians in HNC management.</description><identifier>ISSN: 1555-4309</identifier><identifier>EISSN: 1555-4317</identifier><identifier>DOI: 10.1155/2018/8923028</identifier><identifier>PMID: 30473644</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Accuracy ; Artificial neural networks ; Automation ; Brain cancer ; Cancer ; Cancer therapies ; Computed tomography ; Contouring ; Correlation analysis ; Deep Learning ; Female ; Head &amp; neck cancer ; Head and Neck Neoplasms - diagnostic imaging ; Humans ; Image processing ; Image segmentation ; International conferences ; Male ; Medical imaging ; Methods ; Middle Aged ; Models, Theoretical ; Neural networks ; NMR ; Nuclear magnetic resonance ; Positron emission ; Positron emission tomography ; Positron Emission Tomography Computed Tomography ; Semantics ; Tomography ; Tumors</subject><ispartof>Contrast media and molecular imaging, 2018-01, Vol.2018 (2018), p.1-12</ispartof><rights>Copyright © 2018 Bin Huang et al.</rights><rights>Copyright © 2018 Bin Huang et al. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. http://creativecommons.org/licenses/by/4.0</rights><rights>Copyright © 2018 Bin Huang et al. 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c537t-ced95addd6ffbc4f99de1fb5081cae21a31f3dacbcbf803d738875f86ac0822d3</citedby><cites>FETCH-LOGICAL-c537t-ced95addd6ffbc4f99de1fb5081cae21a31f3dacbcbf803d738875f86ac0822d3</cites><orcidid>0000-0002-1183-7506 ; 0000-0003-2876-4152 ; 0000-0002-9843-475X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220410/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6220410/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/30473644$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><contributor>Pascali, Giancarlo</contributor><contributor>Giancarlo Pascali</contributor><creatorcontrib>Li, Qiaoliang</creatorcontrib><creatorcontrib>Huang, Bingsheng</creatorcontrib><creatorcontrib>Wang, Tian-Fu</creatorcontrib><creatorcontrib>Zheng, Liyun</creatorcontrib><creatorcontrib>Wong, Ching-Yee Oliver</creatorcontrib><creatorcontrib>Feng, Shi-Ting</creatorcontrib><creatorcontrib>Ye, Yufeng</creatorcontrib><creatorcontrib>Wu, Po-Man</creatorcontrib><creatorcontrib>Chen, Zhewei</creatorcontrib><creatorcontrib>Huang, Bin</creatorcontrib><creatorcontrib>Liu, Yong</creatorcontrib><title>Fully Automated Delineation of Gross Tumor Volume for Head and Neck Cancer on PET-CT Using Deep Learning: A Dual-Center Study</title><title>Contrast media and molecular imaging</title><addtitle>Contrast Media Mol Imaging</addtitle><description>Purpose. In this study, we proposed an automated deep learning (DL) method for head and neck cancer (HNC) gross tumor volume (GTV) contouring on positron emission tomography-computed tomography (PET-CT) images. Materials and Methods. PET-CT images were collected from 22 newly diagnosed HNC patients, of whom 17 (Database 1) and 5 (Database 2) were from two centers, respectively. An oncologist and a radiologist decided the gold standard of GTV manually by consensus. We developed a deep convolutional neural network (DCNN) and trained the network based on the two-dimensional PET-CT images and the gold standard of GTV in the training dataset. We did two experiments: Experiment 1, with Database 1 only, and Experiment 2, with both Databases 1 and 2. In both Experiment 1 and Experiment 2, we evaluated the proposed method using a leave-one-out cross-validation strategy. We compared the median results in Experiment 2 (GTVa) with the performance of other methods in the literature and with the gold standard (GTVm). Results. A tumor segmentation task for a patient on coregistered PET-CT images took less than one minute. The dice similarity coefficient (DSC) of the proposed method in Experiment 1 and Experiment 2 was 0.481∼0.872 and 0.482∼0.868, respectively. The DSC of GTVa was better than that in previous studies. A high correlation was found between GTVa and GTVm (R = 0.99, P&lt;0.001). The median volume difference (%) between GTVm and GTVa was 10.9%. The median values of DSC, sensitivity, and precision of GTVa were 0.785, 0.764, and 0.789, respectively. Conclusion. A fully automatic GTV contouring method for HNC based on DCNN and PET-CT from dual centers has been successfully proposed with high accuracy and efficiency. Our proposed method is of help to the clinicians in HNC management.</description><subject>Accuracy</subject><subject>Artificial neural networks</subject><subject>Automation</subject><subject>Brain cancer</subject><subject>Cancer</subject><subject>Cancer therapies</subject><subject>Computed tomography</subject><subject>Contouring</subject><subject>Correlation analysis</subject><subject>Deep Learning</subject><subject>Female</subject><subject>Head &amp; neck cancer</subject><subject>Head and Neck Neoplasms - diagnostic imaging</subject><subject>Humans</subject><subject>Image processing</subject><subject>Image segmentation</subject><subject>International conferences</subject><subject>Male</subject><subject>Medical imaging</subject><subject>Methods</subject><subject>Middle Aged</subject><subject>Models, Theoretical</subject><subject>Neural networks</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Positron emission</subject><subject>Positron emission tomography</subject><subject>Positron Emission Tomography Computed Tomography</subject><subject>Semantics</subject><subject>Tomography</subject><subject>Tumors</subject><issn>1555-4309</issn><issn>1555-4317</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNqNkctv1DAQhyMEoqVw44wscUGCUD_ycDggrdIX0gqQ2HK1Jva4TUnsxYlBe-B_x6tdlseJk8f2559m_GXZU0ZfM1aWp5wyeSobLiiX97LjdFTmhWD1_UNNm6Ps0TTdUVoUohEPsyNBi1pURXGc_biIw7Ahizj7EWY05AyH3iHMvXfEW3IZ_DSRVRx9IJ_9EEckNpVXCIaAM-Q96i-kBacxkPTi4_kqb1fkeurdTYrCNVkiBJd2b8iCnEUY8hbdnOBPczSbx9kDC8OET_brSXZ9cb5qr_Llh8t37WKZ61LUc67RNCUYYyprO13YpjHIbFdSyTQgZyCYFQZ0pzsrqTC1kLIuraxAU8m5ESfZ213uOnYjGp1aCDCodehHCBvloVd_37j-Vt34b6rinBaMpoAX-4Dgv0acZjX2k8ZhAIc-ToozIWlRCS4T-vwf9M7H4NJ4iWpociaqJlGvdpTefnBAe2iGUbX1qrZe1d5rwp_9OcAB_iUyAS93wG3vDHzv_zMOE4MWftNMsIo24icVw7Th</recordid><startdate>20180101</startdate><enddate>20180101</enddate><creator>Li, Qiaoliang</creator><creator>Huang, Bingsheng</creator><creator>Wang, Tian-Fu</creator><creator>Zheng, Liyun</creator><creator>Wong, Ching-Yee Oliver</creator><creator>Feng, Shi-Ting</creator><creator>Ye, Yufeng</creator><creator>Wu, Po-Man</creator><creator>Chen, Zhewei</creator><creator>Huang, Bin</creator><creator>Liu, Yong</creator><general>Hindawi Publishing Corporation</general><general>Hindawi</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QO</scope><scope>7QP</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>BYOGL</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-1183-7506</orcidid><orcidid>https://orcid.org/0000-0003-2876-4152</orcidid><orcidid>https://orcid.org/0000-0002-9843-475X</orcidid></search><sort><creationdate>20180101</creationdate><title>Fully Automated Delineation of Gross Tumor Volume for Head and Neck Cancer on PET-CT Using Deep Learning: A Dual-Center Study</title><author>Li, Qiaoliang ; Huang, Bingsheng ; Wang, Tian-Fu ; Zheng, Liyun ; Wong, Ching-Yee Oliver ; Feng, Shi-Ting ; Ye, Yufeng ; Wu, Po-Man ; Chen, Zhewei ; Huang, Bin ; Liu, Yong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c537t-ced95addd6ffbc4f99de1fb5081cae21a31f3dacbcbf803d738875f86ac0822d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Accuracy</topic><topic>Artificial neural networks</topic><topic>Automation</topic><topic>Brain cancer</topic><topic>Cancer</topic><topic>Cancer therapies</topic><topic>Computed tomography</topic><topic>Contouring</topic><topic>Correlation analysis</topic><topic>Deep Learning</topic><topic>Female</topic><topic>Head &amp; neck cancer</topic><topic>Head and Neck Neoplasms - diagnostic imaging</topic><topic>Humans</topic><topic>Image processing</topic><topic>Image segmentation</topic><topic>International conferences</topic><topic>Male</topic><topic>Medical imaging</topic><topic>Methods</topic><topic>Middle Aged</topic><topic>Models, Theoretical</topic><topic>Neural networks</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Positron emission</topic><topic>Positron emission tomography</topic><topic>Positron Emission Tomography Computed Tomography</topic><topic>Semantics</topic><topic>Tomography</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Li, Qiaoliang</creatorcontrib><creatorcontrib>Huang, Bingsheng</creatorcontrib><creatorcontrib>Wang, Tian-Fu</creatorcontrib><creatorcontrib>Zheng, Liyun</creatorcontrib><creatorcontrib>Wong, Ching-Yee Oliver</creatorcontrib><creatorcontrib>Feng, Shi-Ting</creatorcontrib><creatorcontrib>Ye, Yufeng</creatorcontrib><creatorcontrib>Wu, Po-Man</creatorcontrib><creatorcontrib>Chen, Zhewei</creatorcontrib><creatorcontrib>Huang, Bin</creatorcontrib><creatorcontrib>Liu, Yong</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Biotechnology Research Abstracts</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>East Europe, Central Europe Database</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Contrast media and molecular imaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Li, Qiaoliang</au><au>Huang, Bingsheng</au><au>Wang, Tian-Fu</au><au>Zheng, Liyun</au><au>Wong, Ching-Yee Oliver</au><au>Feng, Shi-Ting</au><au>Ye, Yufeng</au><au>Wu, Po-Man</au><au>Chen, Zhewei</au><au>Huang, Bin</au><au>Liu, Yong</au><au>Pascali, Giancarlo</au><au>Giancarlo Pascali</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fully Automated Delineation of Gross Tumor Volume for Head and Neck Cancer on PET-CT Using Deep Learning: A Dual-Center Study</atitle><jtitle>Contrast media and molecular imaging</jtitle><addtitle>Contrast Media Mol Imaging</addtitle><date>2018-01-01</date><risdate>2018</risdate><volume>2018</volume><issue>2018</issue><spage>1</spage><epage>12</epage><pages>1-12</pages><issn>1555-4309</issn><eissn>1555-4317</eissn><abstract>Purpose. In this study, we proposed an automated deep learning (DL) method for head and neck cancer (HNC) gross tumor volume (GTV) contouring on positron emission tomography-computed tomography (PET-CT) images. Materials and Methods. PET-CT images were collected from 22 newly diagnosed HNC patients, of whom 17 (Database 1) and 5 (Database 2) were from two centers, respectively. An oncologist and a radiologist decided the gold standard of GTV manually by consensus. We developed a deep convolutional neural network (DCNN) and trained the network based on the two-dimensional PET-CT images and the gold standard of GTV in the training dataset. We did two experiments: Experiment 1, with Database 1 only, and Experiment 2, with both Databases 1 and 2. In both Experiment 1 and Experiment 2, we evaluated the proposed method using a leave-one-out cross-validation strategy. We compared the median results in Experiment 2 (GTVa) with the performance of other methods in the literature and with the gold standard (GTVm). Results. A tumor segmentation task for a patient on coregistered PET-CT images took less than one minute. The dice similarity coefficient (DSC) of the proposed method in Experiment 1 and Experiment 2 was 0.481∼0.872 and 0.482∼0.868, respectively. The DSC of GTVa was better than that in previous studies. A high correlation was found between GTVa and GTVm (R = 0.99, P&lt;0.001). The median volume difference (%) between GTVm and GTVa was 10.9%. The median values of DSC, sensitivity, and precision of GTVa were 0.785, 0.764, and 0.789, respectively. Conclusion. A fully automatic GTV contouring method for HNC based on DCNN and PET-CT from dual centers has been successfully proposed with high accuracy and efficiency. Our proposed method is of help to the clinicians in HNC management.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><pmid>30473644</pmid><doi>10.1155/2018/8923028</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-1183-7506</orcidid><orcidid>https://orcid.org/0000-0003-2876-4152</orcidid><orcidid>https://orcid.org/0000-0002-9843-475X</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 1555-4309
ispartof Contrast media and molecular imaging, 2018-01, Vol.2018 (2018), p.1-12
issn 1555-4309
1555-4317
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6220410
source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; PubMed Central; Alma/SFX Local Collection
subjects Accuracy
Artificial neural networks
Automation
Brain cancer
Cancer
Cancer therapies
Computed tomography
Contouring
Correlation analysis
Deep Learning
Female
Head & neck cancer
Head and Neck Neoplasms - diagnostic imaging
Humans
Image processing
Image segmentation
International conferences
Male
Medical imaging
Methods
Middle Aged
Models, Theoretical
Neural networks
NMR
Nuclear magnetic resonance
Positron emission
Positron emission tomography
Positron Emission Tomography Computed Tomography
Semantics
Tomography
Tumors
title Fully Automated Delineation of Gross Tumor Volume for Head and Neck Cancer on PET-CT Using Deep Learning: A Dual-Center Study
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-20T23%3A59%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Fully%20Automated%20Delineation%20of%20Gross%20Tumor%20Volume%20for%20Head%20and%20Neck%20Cancer%20on%20PET-CT%20Using%20Deep%20Learning:%20A%20Dual-Center%20Study&rft.jtitle=Contrast%20media%20and%20molecular%20imaging&rft.au=Li,%20Qiaoliang&rft.date=2018-01-01&rft.volume=2018&rft.issue=2018&rft.spage=1&rft.epage=12&rft.pages=1-12&rft.issn=1555-4309&rft.eissn=1555-4317&rft_id=info:doi/10.1155/2018/8923028&rft_dat=%3Cproquest_pubme%3E2190115369%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2190115369&rft_id=info:pmid/30473644&rfr_iscdi=true