A20-binding inhibitor of NF-κB (ABIN) 2 negatively regulates allergic airway inflammation

TPL-2 MAP 3-kinase promotes inflammation in numerous mouse disease models and is an attractive anti-inflammatory drug target. However, TPL-2-deficient ( ) mice develop exacerbated allergic airway inflammation to house dust mite (HDM) compared with wild type controls. Here, we show that mice expressi...

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