1α,25-dihydroxyvitamin D3-eluting nanofibrous dressings induce endogenous antimicrobial peptide expression

Aim: The aim of this study was to develop a nanofiber-based dressing capable of local sustained delivery of 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) and augmenting human CAMP induction. Materials & methods: Nanofibrous wound dressings containing 1,25(OH)2D3 were successfully prepared by electrosp...

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Veröffentlicht in:	Nanomedicine (London, England) England), 2018-06, Vol.13 (12), p.1417-1432
Hauptverfasser:	Jiang, Jiang, Zhang, Yang, Indra, Arup K, Ganguli-Indra, Gitali, Le, Mai N, Wang, Hongjun, Hollins, Ronald R, Reilly, Debra A, Carlson, Mark A, Gallo, Richard L, Gombart, Adrian F, Xie, Jingwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics Antimicrobial agents Bacterial infections Drug resistance Gene expression Hydrogels Infections Morphology Pathogens Peptides Vitamin D Wound healing
Online-Zugang:	Volltext
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