CD8+ T-Cell Density Imaging with 64Cu-Labeled Cys-Diabody Informs Immunotherapy Protocols

Purpose: Noninvasive and quantitative tracking of CD8+ T cells by PET has emerged as a potential technique to gauge response to immunotherapy. We apply an anti-CD8 cys-diabody, labeled with 64Cu, to assess the sensitivity of PET imaging of normal and diseased tissue. Experimental Design: Radiolabeli...

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Veröffentlicht in:	Clinical cancer research 2018-10, Vol.24 (20), p.4976-4987
Hauptverfasser:	Seo, Jai Woong, Tavaré, Richard, Mahakian, Lisa M., Silvestrini, Matthew T., Tam, Sarah, Ingham, Elizabeth S., Salazar, Felix B., Borowsky, Alexander D., Wu, Anna M., Ferrara, Katherine W.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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