Antioxidant Activity Mediates Pirfenidone Antifibrotic Effects in Human Pulmonary Vascular Smooth Muscle Cells Exposed to Sera of Idiopathic Pulmonary Fibrosis Patients

Idiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterized by an exacerbated fibrotic response. Although molecular and cellular determinants involved in the onset and progression of this devastating disease are largely unknown, an aberrant remodeling of the pulmonary vasculature app...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Oxidative medicine and cellular longevity 2018-01, Vol.2018 (2018), p.1-8
Hauptverfasser:	Pintus, Gianfranco, Zinellu, Angelo, Pirina, Pietro, Rizk, Nasser M., Agouni, Abdelali, Cossu, Annalisa, Giordo, Roberta, Posadino, Anna Maria, Fois, Alessandro G., Carru, Ciriaco
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antioxidants Antioxidants - pharmacology Antioxidants - therapeutic use Biology Biopsy Carbon monoxide Cell adhesion & migration Cell growth Cell Proliferation - drug effects Collagen Collagen Type I - metabolism Development and progression Extracellular matrix Female Fibroblasts Growth factors Humans Idiopathic Pulmonary Fibrosis - blood Kinases Lung diseases Male Muscle, Smooth, Vascular - pathology Myocytes, Smooth Muscle - drug effects Myocytes, Smooth Muscle - metabolism Myocytes, Smooth Muscle - pathology Oxidases Oxidative stress Pathogenesis Pathology Physiology Pulmonary fibrosis Pulmonary Fibrosis - drug therapy Pyridones - pharmacology Pyridones - therapeutic use Reactive Oxygen Species - metabolism Respiratory tract diseases Smooth muscle Tomography
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!