Comprehensive Analysis of Germline Variants in Mexican Patients with Hereditary Breast and Ovarian Cancer Susceptibility

Hereditary breast and ovarian cancer syndrome (HBOC) represents 5⁻10% of all patients with breast cancer and is associated with high-risk pathogenic alleles in genes, but only for 25% of cases. We aimed to find new pathogenic alleles in a panel of 143 cancer-predisposing genes in 300 Mexican cancer...

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Veröffentlicht in:	Cancers 2018-09, Vol.10 (10), p.361
Hauptverfasser:	Quezada Urban, Rosalía, Díaz Velásquez, Clara Estela, Gitler, Rina, Rojo Castillo, María Patricia, Sirota Toporek, Max, Figueroa Morales, Andrea, Moreno García, Oscar, García Esquivel, Lizbeth, Torres Mejía, Gabriela, Dean, Michael, Delgado Enciso, Iván, Ochoa Díaz López, Héctor, Rodríguez León, Fernando, Jan, Virginia, Garzón Barrientos, Víctor Hugo, Ruiz Flores, Pablo, Espino Silva, Perla Karina, Haro Santa Cruz, Jorge, Martínez Gregorio, Héctor, Rojas Jiménez, Ernesto Arturo, Romero Cruz, Luis Enrique, Méndez Catalá, Claudia Fabiola, Álvarez Gómez, Rosa María, Fragoso Ontiveros, Verónica, Herrera, Luis Alonso, Romieu, Isabelle, Terrazas, Luis Ignacio, Chirino, Yolanda Irasema, Frecha, Cecilia, Oliver, Javier, Perdomo, Sandra, Vaca Paniagua, Felipe
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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