Molecular Scoring of Hepatocellular Carcinoma for Predicting Metastatic Recurrence and Requirements of Systemic Chemotherapy

Hepatocellular carcinoma (HCC) causes one of the most frequent cancer-related deaths; an HCC subset shows rapid progression that affects survival. We clarify molecular features of aggressive HCC, and establish a molecular scoring system that predicts metastasis after curative treatment. In total, 12...

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Veröffentlicht in:	Cancers 2018-09, Vol.10 (10), p.367
Hauptverfasser:	Nishida, Naoshi, Nishimura, Takafumi, Kaido, Toshimi, Minaga, Kosuke, Yamao, Kentaro, Kamata, Ken, Takenaka, Mamoru, Ida, Hiroshi, Hagiwara, Satoru, Minami, Yasunori, Sakurai, Toshiharu, Watanabe, Tomohiro, Kudo, Masatoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer therapies Chemotherapy Chromosomes DNA methylation Epigenetics Genes Genomes Genomic instability Genotype & phenotype Growth factors Hepatitis Hepatocellular carcinoma Hepatology Kinases Liver cancer Liver transplantation Males Metastases Metastasis Mutation Nucleotide sequence p53 Protein Patients Phenotypes Risk factors Survival Telomerase Tumor suppressor genes
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