Unliganded Progesterone Receptor Governs Estrogen Receptor Gene Expression by Regulating DNA Methylation in Breast Cancer Cells

Breast cancer prognosis and response to endocrine therapy strongly depends on the expression of the estrogen and progesterone receptors (ER and PR, respectively). Although much is known about ERα gene ( ) regulation after hormonal stimulation, how it is regulated in hormone-free condition is not ful...

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Veröffentlicht in:	Cancers 2018-10, Vol.10 (10), p.371
Hauptverfasser:	Verde, Gaetano, De Llobet, Lara I, Wright, Roni H G, Quilez, Javier, Peiró, Sandra, Le Dily, François, Beato, Miguel
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioinformatics Breast cancer Cell cycle Cloning Deoxyribonucleic acid DNA DNA methylation Endocrine therapy Estrogen receptor Estrogen receptors Experiments Gene expression Genomes Growth factors Hormones Kinases Progesterone Progesterone receptor Progesterone receptors Proteins
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