Persistence With Conventional Triple Therapy Versus a Tumor Necrosis Factor Inhibitor and Methotrexate in US Veterans With Rheumatoid Arthritis

Objective To compare persistence and adherence to triple therapy with the nonbiologic disease‐modifying antirheumatic drugs (DMARDs) methotrexate (MTX), hydroxychloroquine, and sulfasalazine, versus a tumor necrosis factor inhibitor (TNFi) plus MTX in patients with rheumatoid arthritis (RA). Methods...

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Veröffentlicht in:	Arthritis care & research (2010) 2017-03, Vol.69 (3), p.313-322
Hauptverfasser:	Sauer, Brian C., Teng, Chia‐Chen, Tang, Derek, Leng, Jianwei, Curtis, Jeffrey R., Mikuls, Ted R., Harrison, David J., Cannon, Grant W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antirheumatic Agents - adverse effects Antirheumatic Agents - therapeutic use Arthritis, Rheumatoid - diagnosis Arthritis, Rheumatoid - drug therapy Arthritis, Rheumatoid - immunology Biological Products - adverse effects Biological Products - therapeutic use Data processing Databases, Factual Drug Substitution Drug Therapy, Combination Female Humans Hydroxychloroquine Hydroxychloroquine - therapeutic use Kaplan-Meier Estimate Logistic Models Male Medication Adherence Methotrexate Methotrexate - adverse effects Methotrexate - therapeutic use Middle Aged Propensity Score Retrospective Studies Rheumatoid Arthritis Risk Factors Sulfasalazine Sulfasalazine - therapeutic use Time Factors Treatment Outcome Tumor necrosis factor Tumor Necrosis Factor-alpha - antagonists & inhibitors Tumor Necrosis Factor-alpha - immunology Tumor necrosis factor-TNF United States Veterans Health
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