Bisphosphonates-induced Atypical Subtrochanteric Fracture Femur: A Case Report
A 71-year-old female came to our institute with a subtrochanteric left femur fracture following a fall from her bed. It was a low-energy trauma, and the X-rays were suggestive of an atypical fracture following bisphosphonate therapy for five years. The fracture was fixed with intramedullary nailing...
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| Veröffentlicht in: | Curēus (Palo Alto, CA) CA), 2018-07, Vol.10 (7), p.e2937 |
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| creator | Yadav, Siddhart Khanna, Vikram |
| description | A 71-year-old female came to our institute with a subtrochanteric left femur fracture following a fall from her bed. It was a low-energy trauma, and the X-rays were suggestive of an atypical fracture following bisphosphonate therapy for five years. The fracture was fixed with intramedullary nailing following which she was started on partial weight-bearing walking after three weeks. The fracture went on to a nonunion; after one year, the fracture site was opened and bone grafting with bone marrow injection, along with augmented plating, was done. The fracture showed signs of union three months postoperatively. Fractures associated with bisphosphonate therapy may be associated with delayed union or nonunion and should be explained to the patient. |
| doi_str_mv | 10.7759/cureus.2937 |
| format | Article |
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It was a low-energy trauma, and the X-rays were suggestive of an atypical fracture following bisphosphonate therapy for five years. The fracture was fixed with intramedullary nailing following which she was started on partial weight-bearing walking after three weeks. The fracture went on to a nonunion; after one year, the fracture site was opened and bone grafting with bone marrow injection, along with augmented plating, was done. The fracture showed signs of union three months postoperatively. Fractures associated with bisphosphonate therapy may be associated with delayed union or nonunion and should be explained to the patient.</description><identifier>ISSN: 2168-8184</identifier><identifier>EISSN: 2168-8184</identifier><identifier>DOI: 10.7759/cureus.2937</identifier><identifier>PMID: 30397559</identifier><language>eng</language><publisher>United States: Cureus Inc</publisher><subject>Bisphosphonates ; Bone marrow ; Case reports ; Fractures ; Orthopedics ; Osteoporosis ; Pain ; Patients ; Skin & tissue grafts ; Trauma ; X-rays</subject><ispartof>Curēus (Palo Alto, CA), 2018-07, Vol.10 (7), p.e2937</ispartof><rights>Copyright © 2018, Yadav et al. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). 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It was a low-energy trauma, and the X-rays were suggestive of an atypical fracture following bisphosphonate therapy for five years. The fracture was fixed with intramedullary nailing following which she was started on partial weight-bearing walking after three weeks. The fracture went on to a nonunion; after one year, the fracture site was opened and bone grafting with bone marrow injection, along with augmented plating, was done. The fracture showed signs of union three months postoperatively. Fractures associated with bisphosphonate therapy may be associated with delayed union or nonunion and should be explained to the patient.</description><subject>Bisphosphonates</subject><subject>Bone marrow</subject><subject>Case reports</subject><subject>Fractures</subject><subject>Orthopedics</subject><subject>Osteoporosis</subject><subject>Pain</subject><subject>Patients</subject><subject>Skin & tissue grafts</subject><subject>Trauma</subject><subject>X-rays</subject><issn>2168-8184</issn><issn>2168-8184</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><recordid>eNpVkEtLAzEUhYMottSu3MuAS5ma1yQZF0ItVoWi4GMdMpmMndJOxjyE_nuntpa6uNwL93DO4QPgHMER51l-raMz0Y9wTvgR6GPERCqQoMcHdw8MvV9ACBHkGHJ4CnoEkpxnWd4Hz3e1b-d2M40Kxqd1U0ZtymQc1m2t1TJ5i0VwVs9VE4yrdTJ1SocuNZmaVXQ3yTiZKG-SV9NaF87ASaWW3gx3ewA-pvfvk8d09vLwNBnPUo0ZDSnNhaZVyQlhusQaCsgYV5iViHcHNtToshKIQZoJaDQsTM4ZZRXKCgY5R2QAbre-bSxWptSmCU4tZevqlXJraVUt_3-aei4_7bdkHQEsaGdwuTNw9isaH-TCRtd0nSVGJBc5Fb-qq61KO-u9M9U-AUG54S-3_OWGf6e-OCy11_7RJj-yM4JM</recordid><startdate>20180706</startdate><enddate>20180706</enddate><creator>Yadav, Siddhart</creator><creator>Khanna, Vikram</creator><general>Cureus Inc</general><general>Cureus</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>5PM</scope></search><sort><creationdate>20180706</creationdate><title>Bisphosphonates-induced Atypical Subtrochanteric Fracture Femur: A Case Report</title><author>Yadav, Siddhart ; Khanna, Vikram</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c264t-498c4fd7336cd2c080667a26d176672e4ecdf81604580ec0be97646f15b607713</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Bisphosphonates</topic><topic>Bone marrow</topic><topic>Case reports</topic><topic>Fractures</topic><topic>Orthopedics</topic><topic>Osteoporosis</topic><topic>Pain</topic><topic>Patients</topic><topic>Skin & tissue grafts</topic><topic>Trauma</topic><topic>X-rays</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yadav, Siddhart</creatorcontrib><creatorcontrib>Khanna, Vikram</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Curēus (Palo Alto, CA)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yadav, Siddhart</au><au>Khanna, Vikram</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bisphosphonates-induced Atypical Subtrochanteric Fracture Femur: A Case Report</atitle><jtitle>Curēus (Palo Alto, CA)</jtitle><addtitle>Cureus</addtitle><date>2018-07-06</date><risdate>2018</risdate><volume>10</volume><issue>7</issue><spage>e2937</spage><pages>e2937-</pages><issn>2168-8184</issn><eissn>2168-8184</eissn><abstract>A 71-year-old female came to our institute with a subtrochanteric left femur fracture following a fall from her bed. It was a low-energy trauma, and the X-rays were suggestive of an atypical fracture following bisphosphonate therapy for five years. The fracture was fixed with intramedullary nailing following which she was started on partial weight-bearing walking after three weeks. The fracture went on to a nonunion; after one year, the fracture site was opened and bone grafting with bone marrow injection, along with augmented plating, was done. The fracture showed signs of union three months postoperatively. Fractures associated with bisphosphonate therapy may be associated with delayed union or nonunion and should be explained to the patient.</abstract><cop>United States</cop><pub>Cureus Inc</pub><pmid>30397559</pmid><doi>10.7759/cureus.2937</doi><oa>free_for_read</oa></addata></record> |
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| ispartof | Curēus (Palo Alto, CA), 2018-07, Vol.10 (7), p.e2937 |
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| language | eng |
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| source | PubMed Central Open Access; PubMed Central |
| subjects | Bisphosphonates Bone marrow Case reports Fractures Orthopedics Osteoporosis Pain Patients Skin & tissue grafts Trauma X-rays |
| title | Bisphosphonates-induced Atypical Subtrochanteric Fracture Femur: A Case Report |
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