Rerouting of NADPH synthetic pathways for increased protopanaxadiol production in Saccharomyces cerevisiae

Ginseng ( Panax ginseng ) and its bioactive components, ginsenosides, are popular medicinal herbal products, exhibiting various pharmacological effects. Despite their advocated use for medication, the long cultivation periods of ginseng roots and their low ginsenoside content prevent mass production...

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Veröffentlicht in:	Scientific reports 2018-10, Vol.8 (1), p.15820-11, Article 15820
Hauptverfasser:	Kim, Jae-Eung, Jang, In-Seung, Sung, Bong Hyun, Kim, Sun Chang, Lee, Ju Young
Format:	Artikel
Sprache:	eng
Schlagworte:	42/41 42/44 631/61/318 631/61/338/318 Biosynthetic Pathways Carbon - pharmacology Ginseng Ginsenosides Herbal medicine Humanities and Social Sciences Metabolic Engineering multidisciplinary NADP NADP - biosynthesis Oxidation-Reduction Promoter Regions, Genetic - genetics Saccharomyces cerevisiae Saccharomyces cerevisiae - drug effects Saccharomyces cerevisiae - growth & development Saccharomyces cerevisiae - metabolism Sapogenins - chemistry Sapogenins - metabolism Science Science (multidisciplinary) Yeast Yeasts
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