Effect of Intranasal Vasoconstrictors on Blood Pressure: A Randomized, Double-Blind, Placebo-Controlled Trial

Treatment for epistaxis includes application of intranasal vasoconstrictors. These medications have a precaution against use in patients with hypertension. Given that many patients who present with epistaxis are hypertensive, these warnings are commonly overridden by clinical necessity. Our aim was...

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Veröffentlicht in:	The Journal of emergency medicine 2018-10, Vol.55 (4), p.455-464
Hauptverfasser:	Bellew, Shawna D., Johnson, Katie L., Nichols, Micah D., Kummer, Tobias
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intranasal Anesthetics, Local - administration & dosage Anesthetics, Local - pharmacology Anesthetics, Local - therapeutic use Blood Pressure - drug effects Blood Pressure - physiology Double-Blind Method Emergency Service, Hospital - organization & administration epinephrine Epinephrine - administration & dosage Epinephrine - pharmacology Epinephrine - therapeutic use epistaxis Epistaxis - drug therapy Epistaxis - etiology Female hemodynamics Humans Hypertension - complications Hypertension - drug therapy Lidocaine - administration & dosage Lidocaine - pharmacology Lidocaine - therapeutic use Male Nasal Decongestants - administration & dosage Nasal Decongestants - pharmacology Nasal Decongestants - therapeutic use oxymetazoline Oxymetazoline - administration & dosage Oxymetazoline - pharmacology Oxymetazoline - therapeutic use phenylephrine Phenylephrine - administration & dosage Phenylephrine - pharmacology Phenylephrine - therapeutic use Placebos Sodium Chloride - administration & dosage Sodium Chloride - pharmacology Sodium Chloride - therapeutic use Vasoconstrictor Agents - administration & dosage Vasoconstrictor Agents - therapeutic use
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