The caveolae‐associated coiled‐coil protein, NECC2, regulates insulin signalling in Adipocytes

Adipocyte dysfunction in obesity is commonly associated with impaired insulin signalling in adipocytes and insulin resistance. Insulin signalling has been associated with caveolae, which are coated by large complexes of caveolin and cavin proteins, along with proteins with membrane‐binding and remod...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2018-11, Vol.22 (11), p.5648-5661
Hauptverfasser:	Trávez, Andrés, Rabanal‐Ruiz, Yoana, López‐Alcalá, Jaime, Molero‐Murillo, Laura, Díaz‐Ruiz, Alberto, Guzmán‐Ruiz, Rocío, Catalán, Victoria, Rodríguez, Amaia, Frühbeck, Gema, Tinahones, Francisco J., Gasman, Stéphane, Vitale, Nicolas, Jiménez‐Gómez, Yolanda, Malagón, María M.
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3-L1 Cells Adipocytes adipogenesis Adipogenesis - genetics Adipose Tissue - metabolism Adipose Tissue - pathology Animals caveolae Caveolae - metabolism Caveolin 1 - genetics Humans Insulin - genetics insulin resistance Insulin Resistance - genetics insulin signalling Life Sciences Membrane Proteins - genetics Mice Microtubule-Associated Proteins - genetics Microtubule-Associated Proteins - physiology Mitogen-Activated Protein Kinase 1 - genetics NECC2 Neurons and Cognition obesity Obesity - genetics Obesity - metabolism Obesity - pathology Original Phosphorylation Proto-Oncogene Proteins c-akt - genetics Receptor, Insulin - genetics Signal Transduction
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