Single-cell electro-phenotyping for rapid assessment of Clostridium difficile heterogeneity under vancomycin treatment at sub-MIC (minimum inhibitory concentration) levels

[Display omitted] •Microbial-culture independent antibiotic susceptibility assessment using electrophysiology.•Susceptibility to MIC vancomycin levels identified by cytoplasmic conductivity alteration.•Electro-phenotyping based antibiotic susceptibility benchmarked by broth dilution assay.•Rapid ide...

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Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2018-12, Vol.276, p.472-480
Hauptverfasser:	Rohani, Ali, Moore, John H., Su, Yi-Hsuan, Stagnaro, Victoria, Warren, Cirle, Swami, Nathan S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotic Antibiotics Assessments Bacteria Capillary electrophoresis Cells Culture Dielectrophoresis Electrophysiology Electrorotation Measurement methods Microorganisms Minimum inhibitory concentration Single-cell analysis Vancomycin
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