STAT3 promotes tumour progression in glioma by inducing FOXP1 transcription

Objective This paper investigated the effects of STAT3 through promoting FOXP1 transcription on proliferation, apoptosis and invasion in glioma cells. Methods Quantitative real‐time PCR (qRT‐PCR) and Western blot assay were administered to assess the mRNA and protein expression levels of STAT3 and F...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2018-11, Vol.22 (11), p.5629-5638
Hauptverfasser:	Sun, Xinlin, Wang, Jihui, Huang, Min, Chen, Taoliang, Chen, Jiansheng, Zhang, Fabing, Zeng, Huijun, Xu, Zhimin, Ke, Yiquan
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Apoptosis - genetics Cell Cycle - genetics Cell Movement - genetics Cell Proliferation - genetics Female Forkhead Transcription Factors - genetics FOXP1 Gene Expression Regulation, Neoplastic - genetics glioma Glioma - genetics Glioma - pathology Humans Male Middle Aged molecular mechanism Original Repressor Proteins - genetics RNA, Messenger - genetics RNA, Small Interfering - genetics STAT3 STAT3 Transcription Factor - genetics transcription Transcription, Genetic
Online-Zugang:	Volltext
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