LINC00312 represses proliferation and metastasis of colorectal cancer cells by regulation of miR‐21

Long non‐coding RNAs (lncRNAs) have emerged as important regulators of cancer, including colorectal cancer (CRC). The exact expression pattern of long intergenic noncoding RNA 00312 (LINC00312) in CRC and its mechanisms of action have not been reported. Here, we found that LINC00312 is underexpresse...

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Veröffentlicht in:	Journal of cellular and molecular medicine 2018-11, Vol.22 (11), p.5565-5572
Hauptverfasser:	Li, Gang, Wang, Changming, Wang, Yongbing, Xu, Bin, Zhang, Wenzhong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Movement - genetics Cell Proliferation - genetics colorectal cancer Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Gene Expression Regulation, Neoplastic Heterografts HT29 Cells Humans LINC00312 metastasis Mice MicroRNAs - genetics miR‐21 Neoplasm Invasiveness - genetics Neoplasm Invasiveness - pathology Neoplasm Metastasis Original PTEN PTEN Phosphohydrolase - genetics RNA, Long Noncoding - genetics
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