Novel Self-Assembled Micelles Based on Cholesterol-Modified Antimicrobial Peptide (DP7) for Safe and Effective Systemic Administration in Animal Models of Bacterial Infection

Owing to their broad-spectrum antibacterial properties, multitarget effects, and low drug resistance, antimicrobial peptides (AMPs) have played critical roles in the clinical therapy of drug-resistant bacterial infections. However, the potential hazard of hemolysis following systemic administration...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2018-11, Vol.62 (11)
Hauptverfasser:	Zhang, Rui, Wu, Fengbo, Wu, Lei, Tian, Yaomei, Zhou, Bailing, Zhang, Xueyan, Huang, Rong, Yu, Chaoheng, He, Gu, Yang, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents Antimicrobial Cationic Peptides Bacterial Infections Cholesterol Experimental Therapeutics
Online-Zugang:	Volltext
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