In Vitro Liquid Extraction Surface Analysis Mass Spectrometry (ivLESA-MS) for Direct Metabolic Analysis of Adherent Cells in Culture

Conventional metabolomic methods include extensive sample preparation steps and long analytical run times, increasing the likelihood of processing artifacts and limiting high throughput applications. We present here in vitro liquid extraction surface analysis mass spectrometry (ivLESA-MS), a variati...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Analytical chemistry (Washington) 2018-04, Vol.90 (8), p.4987-4991
Hauptverfasser:	Basu, Sankha S, Randall, Elizabeth C, Regan, Michael S, Lopez, Begoña G.C, Clark, Amanda R, Schmitt, Nicholas D, Agar, Jeffrey N, Dillon, Deborah A, Agar, Nathalie Y. R
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Biotechnology Breast cancer Cell culture Cell Line, Tumor Cells Chemistry Chromatography, High Pressure Liquid Culture Media - chemistry Humans In vitro methods and tests Ionization Lipids - analysis Lipids - isolation & purification Liquid-Liquid Extraction Mass spectrometry Metabolites Metabolomics Metabolomics - methods Nanotechnology Negative ions Quenching Spectrometry, Mass, Electrospray Ionization - methods Spectroscopy Surface analysis (chemical) Time dependence
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!