Breast cancer in adolescents and young adults

Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable bio...

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Veröffentlicht in:Pediatric blood & cancer 2018-12, Vol.65 (12), p.e27397-n/a
Hauptverfasser: Johnson, Rebecca H., Anders, Carey K., Litton, Jennifer K., Ruddy, Kathryn J., Bleyer, Archie
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container_issue 12
container_start_page e27397
container_title Pediatric blood & cancer
container_volume 65
creator Johnson, Rebecca H.
Anders, Carey K.
Litton, Jennifer K.
Ruddy, Kathryn J.
Bleyer, Archie
description Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment.
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subjects Adolescent
Adolescents
Adult
age
breast
Breast cancer
Breast Neoplasms - epidemiology
Breast Neoplasms - pathology
Breast Neoplasms - therapy
Cancer therapies
Chemotherapy
Endocrine therapy
Female
Hematology
Hormone replacement therapy
Humans
Invasiveness
Menopause
Metastases
neoplasm
Oncology
Osteoporosis
Pediatrics
pregnancy
Tumors
Womens health
Young Adult
Young adults
title Breast cancer in adolescents and young adults
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