Breast cancer in adolescents and young adults
Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable bio...
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Veröffentlicht in: | Pediatric blood & cancer 2018-12, Vol.65 (12), p.e27397-n/a |
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description | Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment. |
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In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment.</description><subject>Adolescent</subject><subject>Adolescents</subject><subject>Adult</subject><subject>age</subject><subject>breast</subject><subject>Breast cancer</subject><subject>Breast Neoplasms - epidemiology</subject><subject>Breast Neoplasms - pathology</subject><subject>Breast Neoplasms - therapy</subject><subject>Cancer therapies</subject><subject>Chemotherapy</subject><subject>Endocrine therapy</subject><subject>Female</subject><subject>Hematology</subject><subject>Hormone replacement therapy</subject><subject>Humans</subject><subject>Invasiveness</subject><subject>Menopause</subject><subject>Metastases</subject><subject>neoplasm</subject><subject>Oncology</subject><subject>Osteoporosis</subject><subject>Pediatrics</subject><subject>pregnancy</subject><subject>Tumors</subject><subject>Womens health</subject><subject>Young Adult</subject><subject>Young adults</subject><issn>1545-5009</issn><issn>1545-5017</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kUtLAzEUhYMotlYX_gEZcKOLaZNMnhvBFl9Q0IWuQyaT1CnTmZp0lP57U6cWFVzlkvtx7rn3AHCK4BBBiEfL3AwxzyTfA31ECU0pRHx_V0PZA0chzCPKIBWHoJdBRGOJ-yAde6vDKjG6NtYnZZ3ooqlsMLZehUTXRbJu2noWf9tqFY7BgdNVsCfbdwBebm-eJ_fp9PHuYXI9TQ0hGU_zIi-ExEJYAjMmjXZOZi7nlkipiWGaMYkdtbl2iFhuiBAGFhY6ZyiH2GQDcNXpLtt8YYuNGa8rtfTlQvu1anSpfnfq8lXNmnfFUByb4ShwsRXwzVtrw0otyrhTVenaNm1QGEpGKRIZj-j5H3TetL6O6ymMMOSCMCYiddlRxjcheOt2ZhBUmxBUDEF9hRDZs5_ud-T31SMw6oCPsrLr_5XU03jSSX4C6vKQoA</recordid><startdate>201812</startdate><enddate>201812</enddate><creator>Johnson, Rebecca H.</creator><creator>Anders, Carey K.</creator><creator>Litton, Jennifer K.</creator><creator>Ruddy, Kathryn J.</creator><creator>Bleyer, Archie</creator><general>Wiley Subscription Services, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7T5</scope><scope>7TK</scope><scope>7TO</scope><scope>8FD</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-1222-9019</orcidid><orcidid>https://orcid.org/0000-0001-7738-5146</orcidid></search><sort><creationdate>201812</creationdate><title>Breast cancer in adolescents and young adults</title><author>Johnson, Rebecca H. ; Anders, Carey K. ; Litton, Jennifer K. ; Ruddy, Kathryn J. ; Bleyer, Archie</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4437-bdbd89288e40369caff93fb7e499a4c6a6692f5ebaf14e7c488c0de0ffc5702c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adolescent</topic><topic>Adolescents</topic><topic>Adult</topic><topic>age</topic><topic>breast</topic><topic>Breast cancer</topic><topic>Breast Neoplasms - epidemiology</topic><topic>Breast Neoplasms - pathology</topic><topic>Breast Neoplasms - therapy</topic><topic>Cancer therapies</topic><topic>Chemotherapy</topic><topic>Endocrine therapy</topic><topic>Female</topic><topic>Hematology</topic><topic>Hormone replacement therapy</topic><topic>Humans</topic><topic>Invasiveness</topic><topic>Menopause</topic><topic>Metastases</topic><topic>neoplasm</topic><topic>Oncology</topic><topic>Osteoporosis</topic><topic>Pediatrics</topic><topic>pregnancy</topic><topic>Tumors</topic><topic>Womens health</topic><topic>Young Adult</topic><topic>Young adults</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Johnson, Rebecca H.</creatorcontrib><creatorcontrib>Anders, Carey K.</creatorcontrib><creatorcontrib>Litton, Jennifer K.</creatorcontrib><creatorcontrib>Ruddy, Kathryn J.</creatorcontrib><creatorcontrib>Bleyer, Archie</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Pediatric blood & cancer</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Johnson, Rebecca H.</au><au>Anders, Carey K.</au><au>Litton, Jennifer K.</au><au>Ruddy, Kathryn J.</au><au>Bleyer, Archie</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Breast cancer in adolescents and young adults</atitle><jtitle>Pediatric blood & cancer</jtitle><addtitle>Pediatr Blood Cancer</addtitle><date>2018-12</date><risdate>2018</risdate><volume>65</volume><issue>12</issue><spage>e27397</spage><epage>n/a</epage><pages>e27397-n/a</pages><issn>1545-5009</issn><eissn>1545-5017</eissn><abstract>Breast cancer is the most common cancer of adolescents and young adult (AYA) women aged 15 to 39 years, accounting for 5.6% of all invasive breast cancer in women. In comparison with older women, AYAs are more likely to have familial cancer predisposition genes, larger breast tumors, unfavorable biological characteristics, distant metastatic disease at diagnosis, and adverse outcome. Endocrine therapy and some chemotherapy recommendations differ between young and older women. AYAs require coordinated multidisciplinary care, treatment regimens that minimize late effects such as premature menopause and osteoporosis, and proactive management of psychological and sexual health during and after cancer treatment.</abstract><cop>United States</cop><pub>Wiley Subscription Services, Inc</pub><pmid>30156052</pmid><doi>10.1002/pbc.27397</doi><tpages>9</tpages><orcidid>https://orcid.org/0000-0002-1222-9019</orcidid><orcidid>https://orcid.org/0000-0001-7738-5146</orcidid><oa>free_for_read</oa></addata></record> |
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subjects | Adolescent Adolescents Adult age breast Breast cancer Breast Neoplasms - epidemiology Breast Neoplasms - pathology Breast Neoplasms - therapy Cancer therapies Chemotherapy Endocrine therapy Female Hematology Hormone replacement therapy Humans Invasiveness Menopause Metastases neoplasm Oncology Osteoporosis Pediatrics pregnancy Tumors Womens health Young Adult Young adults |
title | Breast cancer in adolescents and young adults |
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