Lrig1 marks a population of gastric epithelial cells capable of long-term tissue maintenance and growth in vitro

The processes involved in renewal of the epithelium that lines the mouse stomach remain unclear. Apart from the cells in the isthmus, several other populations located deeper in the gastric glands have been suggested to contribute to the maintenance of the gastric epithelium. Here, we reveal that Lr...

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Veröffentlicht in:	Scientific reports 2018-10, Vol.8 (1), p.15255-11, Article 15255
Hauptverfasser:	Schweiger, Pawel J., Clement, Ditte L., Page, Mahalia E., Schepeler, Troels, Zou, Xiangang, Sirokmány, Gabor, Watt, Fiona M., Jensen, Kim B.
Format:	Artikel
Sprache:	eng
Schlagworte:	13/100 13/106 14 631/136/532/2118/2437 631/532/2118/2437 64/110 Acidification Animals Biomarkers - metabolism Cell Dedifferentiation - genetics Cell Differentiation - genetics Cell fate Cell Proliferation - genetics Cells, Cultured Enzymes Epithelial cells Epithelial Cells - cytology Epithelial Cells - metabolism Epithelial Cells - physiology Epithelium Fate maps Gastric glands Gastric Mucosa - cytology Gastric Mucosa - metabolism Glands Humanities and Social Sciences Membrane Glycoproteins - physiology Mice Mice, Inbred C57BL Mice, Transgenic multidisciplinary Nerve Tissue Proteins - physiology Organoids Population Science Science (multidisciplinary) Small intestine Stem cells Stomach Stomach - cytology
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