Regulation of Blood Pressure by Targeting CaV1.2-Galectin-1 Protein Interaction

BACKGROUND:L-type CaV1.2 channels play crucial roles in the regulation of blood pressure. Galectin-1 (Gal-1) has been reported to bind to the I-II loop of CaV1.2 channels to reduce their current density. However, the mechanistic understanding for the downregulation of CaV1.2 channels by Gal-1 and wh...

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Veröffentlicht in:	Circulation (New York, N.Y.) N.Y.), 2018-10, Vol.138 (14), p.1431-1445
Hauptverfasser:	Hu, Zhenyu, Li, Guang, Wang, Jiong-Wei, Chong, Suet Yen, Yu, Dejie, Wang, Xiaoyuan, Soon, Jia Lin, Liang, Mui Cheng, Wong, Yuk Peng, Huang, Na, Colecraft, Henry M, Liao, Ping, Soong, Tuck Wah
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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