Loop permutation affects the topology and stability of G-quadruplexes

Abstract G-quadruplexes are unusual DNA and RNA secondary structures ubiquitous in a variety of organisms including vertebrates, plants, viruses and bacteria. The folding topology and stability of intramolecular G-quadruplexes are determined to a large extent by their loops. Loop permutation is defi...

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Veröffentlicht in:Nucleic acids research 2018-10, Vol.46 (18), p.9264-9275
Hauptverfasser: Cheng, Mingpan, Cheng, Yu, Hao, Jingya, Jia, Guoqing, Zhou, Jun, Mergny, Jean-Louis, Li, Can
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Sprache:eng
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