Differences in genomic abnormalities among African individuals with monoclonal gammopathies using calculated ancestry

Multiple myeloma (MM) is two- to three-fold more common in African Americans (AAs) compared to European Americans (EAs). This striking disparity, one of the highest of any cancer, may be due to underlying genetic predisposition between these groups. There are multiple unique cytogenetic subtypes of...

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Veröffentlicht in:	Blood cancer journal (New York) 2018-10, Vol.8 (10), p.96-10, Article 96
Hauptverfasser:	Baughn, Linda B., Pearce, Kathryn, Larson, Dirk, Polley, Mei-Yin, Elhaik, Eran, Baird, Michael, Colby, Colin, Benson, Joanne, Li, Zhuo, Asmann, Yan, Therneau, Terry, Cerhan, James R., Vachon, Celine M., Stewart, A. Keith, Bergsagel, P. Leif, Dispenzieri, Angela, Kumar, Shaji, Rajkumar, S. Vincent
Format:	Artikel
Sprache:	eng
Schlagworte:	13/106 14/32 45/22 45/43 631/208/1405 631/67/68 Adult Aged Aged, 80 and over Biomedical and Life Sciences Biomedicine Black or African American Black People - genetics Cancer Research Chromosome Aberrations Chromosome Banding Disease Progression Female Gene Rearrangement Genes, myc Genetic Variation Hematology Humans In Situ Hybridization, Fluorescence Male Middle Aged Odds Ratio Oncology Paraproteinemias - diagnosis Paraproteinemias - genetics
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