Degranulation of mast cells induced by gastric cancer-derived adrenomedullin prompts gastric cancer progression

Mast cells are prominent components of solid tumors and exhibit distinct phenotypes in different tumor microenvironments. However, their precise mechanism of communication in gastric cancer remains largely unclear. Here, we found that patients with GC showed a significantly higher mast cell infiltra...

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Veröffentlicht in:	Cell death & disease 2018-10, Vol.9 (10), p.1034-12, Article 1034
Hauptverfasser:	Lv, Yi-pin, Peng, Liu-sheng, Wang, Qi-hong, Chen, Na, Teng, Yong-sheng, Wang, Ting-ting, Mao, Fang-yuan, Zhang, Jin-yu, Cheng, Ping, Liu, Yu-gang, Kong, Hui, Wu, Xiao-long, Hao, Chuan-jie, Chen, Weisan, Zhu, Jiang, Han, Bin, Ma, Qiang, Li, Ke, Zou, Quanming, Zhuang, Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase 13/1 13/105 13/106 13/2 13/21 13/31 13/51 42/100 64/60 96/95 Adrenomedullin AKT protein Antibodies Apoptosis Biochemistry Biomedical and Life Sciences Cell Biology Cell Culture Cell proliferation Degranulation Gastric cancer Histamine Immunology Immunopathogenesis Life Sciences Mast cells Metastases Microenvironments Phenotypes Signal transduction Solid tumors Tumors
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