A comparison of the resection rate for cold and hot snare polypectomy for 4–9 mm colorectal polyps: a multicentre randomised controlled trial (CRESCENT study)

ObjectiveTo investigate the success rate of cold snare polypectomy (CSP) for complete resection of 4–9 mm colorectal adenomatous polyps compared with that of hot snare polypectomy (HSP).DesignA prospective, multicentre, randomised controlled, parallel, non-inferiority trial conducted in 12 Japanese...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Gut 2018-11, Vol.67 (11), p.1950-1957
Hauptverfasser: Kawamura, Takuji, Takeuchi, Yoji, Asai, Satoshi, Yokota, Isao, Akamine, Eisuke, Kato, Minoru, Akamatsu, Takuji, Tada, Kazuhiro, Komeda, Yoriaki, Iwatate, Mineo, Kawakami, Ken, Nishikawa, Michiko, Watanabe, Daisuke, Yamauchi, Atsushi, Fukata, Norimasa, Shimatani, Masaaki, Ooi, Makoto, Fujita, Koichi, Sano, Yasushi, Kashida, Hiroshi, Hirose, Satoru, Iwagami, Hiroyoshi, Uedo, Noriya, Teramukai, Satoshi, Tanaka, Kiyohito
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1957
container_issue 11
container_start_page 1950
container_title Gut
container_volume 67
creator Kawamura, Takuji
Takeuchi, Yoji
Asai, Satoshi
Yokota, Isao
Akamine, Eisuke
Kato, Minoru
Akamatsu, Takuji
Tada, Kazuhiro
Komeda, Yoriaki
Iwatate, Mineo
Kawakami, Ken
Nishikawa, Michiko
Watanabe, Daisuke
Yamauchi, Atsushi
Fukata, Norimasa
Shimatani, Masaaki
Ooi, Makoto
Fujita, Koichi
Sano, Yasushi
Kashida, Hiroshi
Hirose, Satoru
Iwagami, Hiroyoshi
Uedo, Noriya
Teramukai, Satoshi
Tanaka, Kiyohito
description ObjectiveTo investigate the success rate of cold snare polypectomy (CSP) for complete resection of 4–9 mm colorectal adenomatous polyps compared with that of hot snare polypectomy (HSP).DesignA prospective, multicentre, randomised controlled, parallel, non-inferiority trial conducted in 12 Japanese endoscopy units. Endoscopically diagnosed sessile adenomatous polyps, 4–9 mm in size, were randomly assigned to the CSP or HSP group. After complete removal of the polyp using the allocated technique, biopsy specimens from the resection margin after polypectomy were obtained. The primary endpoint was the complete resection rate, defined as no evidence of adenomatous tissue in the biopsied specimens, among all pathologically confirmed adenomatous polyps.ResultsA total of 796 eligible polyps were detected in 538 of 912 patients screened for eligibility between September 2015 and August 2016. The complete resection rate for CSP was 98.2% compared with 97.4% for HSP. The non-inferiority of CSP for complete resection compared with HSP was confirmed by the +0.8% (90% CI −1.0 to 2.7) complete resection rate (non-inferiority p
doi_str_mv 10.1136/gutjnl-2017-314215
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6176523</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2117303896</sourcerecordid><originalsourceid>FETCH-LOGICAL-b551t-5384069900883bb7d0fd566212f13907418ce33c5b91ebf9cc31a09c65780cb33</originalsourceid><addsrcrecordid>eNqNks1u1DAUhSMEokPhBVggS2zaRYqvHSc2i0rVaPiRKpCgrC3HcToZOXGwHaTZ8Q59AZ6NJ8FpyvCzQKxs-X7n6B75ZNlTwGcAtHxxPcXdYHOCocopFATYvWwFRclzSji_n63wPGFVIY6yRyHsMMacC3iYHREuKkwEXmXfLpB2_ah8F9yAXIvi1iBvgtGxSw9eRYNa5xNkG6SGBm1dRGFQ3qDR2f2YONfvb5Hi-9cbgfp-Zp1PA2UXJrxECvWTjZ02Q0xKn4xc3wXTJDa9OGvTNfouKU7WHzYf15t3VyjEqdmfPs4etMoG8-TuPM4-vdpcrd_kl-9fv11fXOY1YxBzRnmBSyHmiLSuqwa3DStLAqQFKnBVANeGUs1qAaZuhdYUFBa6ZBXHuqb0ODtffMep7k1zu6mycvRdr_xeOtXJPydDt5XX7ossoSoZmQ1O7gy8-zyZEGVKqI21ajBuChJEURaEAYOEPv8L3bnJDymeJAAVxZSLMlFkobR3IXjTHpYBLOcCyKUAci6AXAqQRM9-j3GQ_PzxBOQLUPe7_zM8-8Uf1vyH4AcfTc0U</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2117303896</pqid></control><display><type>article</type><title>A comparison of the resection rate for cold and hot snare polypectomy for 4–9 mm colorectal polyps: a multicentre randomised controlled trial (CRESCENT study)</title><source>PubMed Central</source><creator>Kawamura, Takuji ; Takeuchi, Yoji ; Asai, Satoshi ; Yokota, Isao ; Akamine, Eisuke ; Kato, Minoru ; Akamatsu, Takuji ; Tada, Kazuhiro ; Komeda, Yoriaki ; Iwatate, Mineo ; Kawakami, Ken ; Nishikawa, Michiko ; Watanabe, Daisuke ; Yamauchi, Atsushi ; Fukata, Norimasa ; Shimatani, Masaaki ; Ooi, Makoto ; Fujita, Koichi ; Sano, Yasushi ; Kashida, Hiroshi ; Hirose, Satoru ; Iwagami, Hiroyoshi ; Uedo, Noriya ; Teramukai, Satoshi ; Tanaka, Kiyohito</creator><creatorcontrib>Kawamura, Takuji ; Takeuchi, Yoji ; Asai, Satoshi ; Yokota, Isao ; Akamine, Eisuke ; Kato, Minoru ; Akamatsu, Takuji ; Tada, Kazuhiro ; Komeda, Yoriaki ; Iwatate, Mineo ; Kawakami, Ken ; Nishikawa, Michiko ; Watanabe, Daisuke ; Yamauchi, Atsushi ; Fukata, Norimasa ; Shimatani, Masaaki ; Ooi, Makoto ; Fujita, Koichi ; Sano, Yasushi ; Kashida, Hiroshi ; Hirose, Satoru ; Iwagami, Hiroyoshi ; Uedo, Noriya ; Teramukai, Satoshi ; Tanaka, Kiyohito</creatorcontrib><description>ObjectiveTo investigate the success rate of cold snare polypectomy (CSP) for complete resection of 4–9 mm colorectal adenomatous polyps compared with that of hot snare polypectomy (HSP).DesignA prospective, multicentre, randomised controlled, parallel, non-inferiority trial conducted in 12 Japanese endoscopy units. Endoscopically diagnosed sessile adenomatous polyps, 4–9 mm in size, were randomly assigned to the CSP or HSP group. After complete removal of the polyp using the allocated technique, biopsy specimens from the resection margin after polypectomy were obtained. The primary endpoint was the complete resection rate, defined as no evidence of adenomatous tissue in the biopsied specimens, among all pathologically confirmed adenomatous polyps.ResultsA total of 796 eligible polyps were detected in 538 of 912 patients screened for eligibility between September 2015 and August 2016. The complete resection rate for CSP was 98.2% compared with 97.4% for HSP. The non-inferiority of CSP for complete resection compared with HSP was confirmed by the +0.8% (90% CI −1.0 to 2.7) complete resection rate (non-inferiority p&lt;0.0001). Postoperative bleeding requiring endoscopic haemostasis occurred only in the HSP group (0.5%, 2 of 402 polyps).ConclusionsThe complete resection rate for CSP is not inferior to that for HSP. CSP can be one of the standard techniques for 4–9 mm colorectal polyps. (Study registration: UMIN000018328)</description><identifier>ISSN: 0017-5749</identifier><identifier>EISSN: 1468-3288</identifier><identifier>DOI: 10.1136/gutjnl-2017-314215</identifier><identifier>PMID: 28970290</identifier><language>eng</language><publisher>England: BMJ Publishing Group Ltd and British Society of Gastroenterology</publisher><subject>Biopsy ; Classification ; Clinical medicine ; Cold ; Colon ; colonic polyps ; Colonoscopy ; Colorectal cancer ; colorectal neoplasm ; Endoscopy ; Gastroenterology ; Generalized linear models ; Polyps ; Tumors</subject><ispartof>Gut, 2018-11, Vol.67 (11), p.1950-1957</ispartof><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.</rights><rights>2018 Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><rights>Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. 2018</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b551t-5384069900883bb7d0fd566212f13907418ce33c5b91ebf9cc31a09c65780cb33</citedby><cites>FETCH-LOGICAL-b551t-5384069900883bb7d0fd566212f13907418ce33c5b91ebf9cc31a09c65780cb33</cites><orcidid>0000-0002-1155-3116 ; 0000-0002-6826-9829</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176523/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176523/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,27901,27902,53766,53768</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/28970290$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kawamura, Takuji</creatorcontrib><creatorcontrib>Takeuchi, Yoji</creatorcontrib><creatorcontrib>Asai, Satoshi</creatorcontrib><creatorcontrib>Yokota, Isao</creatorcontrib><creatorcontrib>Akamine, Eisuke</creatorcontrib><creatorcontrib>Kato, Minoru</creatorcontrib><creatorcontrib>Akamatsu, Takuji</creatorcontrib><creatorcontrib>Tada, Kazuhiro</creatorcontrib><creatorcontrib>Komeda, Yoriaki</creatorcontrib><creatorcontrib>Iwatate, Mineo</creatorcontrib><creatorcontrib>Kawakami, Ken</creatorcontrib><creatorcontrib>Nishikawa, Michiko</creatorcontrib><creatorcontrib>Watanabe, Daisuke</creatorcontrib><creatorcontrib>Yamauchi, Atsushi</creatorcontrib><creatorcontrib>Fukata, Norimasa</creatorcontrib><creatorcontrib>Shimatani, Masaaki</creatorcontrib><creatorcontrib>Ooi, Makoto</creatorcontrib><creatorcontrib>Fujita, Koichi</creatorcontrib><creatorcontrib>Sano, Yasushi</creatorcontrib><creatorcontrib>Kashida, Hiroshi</creatorcontrib><creatorcontrib>Hirose, Satoru</creatorcontrib><creatorcontrib>Iwagami, Hiroyoshi</creatorcontrib><creatorcontrib>Uedo, Noriya</creatorcontrib><creatorcontrib>Teramukai, Satoshi</creatorcontrib><creatorcontrib>Tanaka, Kiyohito</creatorcontrib><title>A comparison of the resection rate for cold and hot snare polypectomy for 4–9 mm colorectal polyps: a multicentre randomised controlled trial (CRESCENT study)</title><title>Gut</title><addtitle>Gut</addtitle><addtitle>Gut</addtitle><description>ObjectiveTo investigate the success rate of cold snare polypectomy (CSP) for complete resection of 4–9 mm colorectal adenomatous polyps compared with that of hot snare polypectomy (HSP).DesignA prospective, multicentre, randomised controlled, parallel, non-inferiority trial conducted in 12 Japanese endoscopy units. Endoscopically diagnosed sessile adenomatous polyps, 4–9 mm in size, were randomly assigned to the CSP or HSP group. After complete removal of the polyp using the allocated technique, biopsy specimens from the resection margin after polypectomy were obtained. The primary endpoint was the complete resection rate, defined as no evidence of adenomatous tissue in the biopsied specimens, among all pathologically confirmed adenomatous polyps.ResultsA total of 796 eligible polyps were detected in 538 of 912 patients screened for eligibility between September 2015 and August 2016. The complete resection rate for CSP was 98.2% compared with 97.4% for HSP. The non-inferiority of CSP for complete resection compared with HSP was confirmed by the +0.8% (90% CI −1.0 to 2.7) complete resection rate (non-inferiority p&lt;0.0001). Postoperative bleeding requiring endoscopic haemostasis occurred only in the HSP group (0.5%, 2 of 402 polyps).ConclusionsThe complete resection rate for CSP is not inferior to that for HSP. CSP can be one of the standard techniques for 4–9 mm colorectal polyps. (Study registration: UMIN000018328)</description><subject>Biopsy</subject><subject>Classification</subject><subject>Clinical medicine</subject><subject>Cold</subject><subject>Colon</subject><subject>colonic polyps</subject><subject>Colonoscopy</subject><subject>Colorectal cancer</subject><subject>colorectal neoplasm</subject><subject>Endoscopy</subject><subject>Gastroenterology</subject><subject>Generalized linear models</subject><subject>Polyps</subject><subject>Tumors</subject><issn>0017-5749</issn><issn>1468-3288</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>9YT</sourceid><sourceid>ACMMV</sourceid><sourceid>BENPR</sourceid><recordid>eNqNks1u1DAUhSMEokPhBVggS2zaRYqvHSc2i0rVaPiRKpCgrC3HcToZOXGwHaTZ8Q59AZ6NJ8FpyvCzQKxs-X7n6B75ZNlTwGcAtHxxPcXdYHOCocopFATYvWwFRclzSji_n63wPGFVIY6yRyHsMMacC3iYHREuKkwEXmXfLpB2_ah8F9yAXIvi1iBvgtGxSw9eRYNa5xNkG6SGBm1dRGFQ3qDR2f2YONfvb5Hi-9cbgfp-Zp1PA2UXJrxECvWTjZ02Q0xKn4xc3wXTJDa9OGvTNfouKU7WHzYf15t3VyjEqdmfPs4etMoG8-TuPM4-vdpcrd_kl-9fv11fXOY1YxBzRnmBSyHmiLSuqwa3DStLAqQFKnBVANeGUs1qAaZuhdYUFBa6ZBXHuqb0ODtffMep7k1zu6mycvRdr_xeOtXJPydDt5XX7ossoSoZmQ1O7gy8-zyZEGVKqI21ajBuChJEURaEAYOEPv8L3bnJDymeJAAVxZSLMlFkobR3IXjTHpYBLOcCyKUAci6AXAqQRM9-j3GQ_PzxBOQLUPe7_zM8-8Uf1vyH4AcfTc0U</recordid><startdate>20181101</startdate><enddate>20181101</enddate><creator>Kawamura, Takuji</creator><creator>Takeuchi, Yoji</creator><creator>Asai, Satoshi</creator><creator>Yokota, Isao</creator><creator>Akamine, Eisuke</creator><creator>Kato, Minoru</creator><creator>Akamatsu, Takuji</creator><creator>Tada, Kazuhiro</creator><creator>Komeda, Yoriaki</creator><creator>Iwatate, Mineo</creator><creator>Kawakami, Ken</creator><creator>Nishikawa, Michiko</creator><creator>Watanabe, Daisuke</creator><creator>Yamauchi, Atsushi</creator><creator>Fukata, Norimasa</creator><creator>Shimatani, Masaaki</creator><creator>Ooi, Makoto</creator><creator>Fujita, Koichi</creator><creator>Sano, Yasushi</creator><creator>Kashida, Hiroshi</creator><creator>Hirose, Satoru</creator><creator>Iwagami, Hiroyoshi</creator><creator>Uedo, Noriya</creator><creator>Teramukai, Satoshi</creator><creator>Tanaka, Kiyohito</creator><general>BMJ Publishing Group Ltd and British Society of Gastroenterology</general><general>BMJ Publishing Group LTD</general><general>BMJ Publishing Group</general><scope>9YT</scope><scope>ACMMV</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>88I</scope><scope>8AF</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BTHHO</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PHGZM</scope><scope>PHGZT</scope><scope>PJZUB</scope><scope>PKEHL</scope><scope>PPXIY</scope><scope>PQEST</scope><scope>PQGLB</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-1155-3116</orcidid><orcidid>https://orcid.org/0000-0002-6826-9829</orcidid></search><sort><creationdate>20181101</creationdate><title>A comparison of the resection rate for cold and hot snare polypectomy for 4–9 mm colorectal polyps: a multicentre randomised controlled trial (CRESCENT study)</title><author>Kawamura, Takuji ; Takeuchi, Yoji ; Asai, Satoshi ; Yokota, Isao ; Akamine, Eisuke ; Kato, Minoru ; Akamatsu, Takuji ; Tada, Kazuhiro ; Komeda, Yoriaki ; Iwatate, Mineo ; Kawakami, Ken ; Nishikawa, Michiko ; Watanabe, Daisuke ; Yamauchi, Atsushi ; Fukata, Norimasa ; Shimatani, Masaaki ; Ooi, Makoto ; Fujita, Koichi ; Sano, Yasushi ; Kashida, Hiroshi ; Hirose, Satoru ; Iwagami, Hiroyoshi ; Uedo, Noriya ; Teramukai, Satoshi ; Tanaka, Kiyohito</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-b551t-5384069900883bb7d0fd566212f13907418ce33c5b91ebf9cc31a09c65780cb33</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Biopsy</topic><topic>Classification</topic><topic>Clinical medicine</topic><topic>Cold</topic><topic>Colon</topic><topic>colonic polyps</topic><topic>Colonoscopy</topic><topic>Colorectal cancer</topic><topic>colorectal neoplasm</topic><topic>Endoscopy</topic><topic>Gastroenterology</topic><topic>Generalized linear models</topic><topic>Polyps</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kawamura, Takuji</creatorcontrib><creatorcontrib>Takeuchi, Yoji</creatorcontrib><creatorcontrib>Asai, Satoshi</creatorcontrib><creatorcontrib>Yokota, Isao</creatorcontrib><creatorcontrib>Akamine, Eisuke</creatorcontrib><creatorcontrib>Kato, Minoru</creatorcontrib><creatorcontrib>Akamatsu, Takuji</creatorcontrib><creatorcontrib>Tada, Kazuhiro</creatorcontrib><creatorcontrib>Komeda, Yoriaki</creatorcontrib><creatorcontrib>Iwatate, Mineo</creatorcontrib><creatorcontrib>Kawakami, Ken</creatorcontrib><creatorcontrib>Nishikawa, Michiko</creatorcontrib><creatorcontrib>Watanabe, Daisuke</creatorcontrib><creatorcontrib>Yamauchi, Atsushi</creatorcontrib><creatorcontrib>Fukata, Norimasa</creatorcontrib><creatorcontrib>Shimatani, Masaaki</creatorcontrib><creatorcontrib>Ooi, Makoto</creatorcontrib><creatorcontrib>Fujita, Koichi</creatorcontrib><creatorcontrib>Sano, Yasushi</creatorcontrib><creatorcontrib>Kashida, Hiroshi</creatorcontrib><creatorcontrib>Hirose, Satoru</creatorcontrib><creatorcontrib>Iwagami, Hiroyoshi</creatorcontrib><creatorcontrib>Uedo, Noriya</creatorcontrib><creatorcontrib>Teramukai, Satoshi</creatorcontrib><creatorcontrib>Tanaka, Kiyohito</creatorcontrib><collection>BMJ Open Access Journals</collection><collection>BMJ Journals:Open Access</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>STEM Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>BMJ Journals</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>ProQuest Central (New)</collection><collection>ProQuest One Academic (New)</collection><collection>ProQuest Health &amp; Medical Research Collection</collection><collection>ProQuest One Academic Middle East (New)</collection><collection>ProQuest One Health &amp; Nursing</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Applied &amp; Life Sciences</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Gut</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kawamura, Takuji</au><au>Takeuchi, Yoji</au><au>Asai, Satoshi</au><au>Yokota, Isao</au><au>Akamine, Eisuke</au><au>Kato, Minoru</au><au>Akamatsu, Takuji</au><au>Tada, Kazuhiro</au><au>Komeda, Yoriaki</au><au>Iwatate, Mineo</au><au>Kawakami, Ken</au><au>Nishikawa, Michiko</au><au>Watanabe, Daisuke</au><au>Yamauchi, Atsushi</au><au>Fukata, Norimasa</au><au>Shimatani, Masaaki</au><au>Ooi, Makoto</au><au>Fujita, Koichi</au><au>Sano, Yasushi</au><au>Kashida, Hiroshi</au><au>Hirose, Satoru</au><au>Iwagami, Hiroyoshi</au><au>Uedo, Noriya</au><au>Teramukai, Satoshi</au><au>Tanaka, Kiyohito</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comparison of the resection rate for cold and hot snare polypectomy for 4–9 mm colorectal polyps: a multicentre randomised controlled trial (CRESCENT study)</atitle><jtitle>Gut</jtitle><stitle>Gut</stitle><addtitle>Gut</addtitle><date>2018-11-01</date><risdate>2018</risdate><volume>67</volume><issue>11</issue><spage>1950</spage><epage>1957</epage><pages>1950-1957</pages><issn>0017-5749</issn><eissn>1468-3288</eissn><abstract>ObjectiveTo investigate the success rate of cold snare polypectomy (CSP) for complete resection of 4–9 mm colorectal adenomatous polyps compared with that of hot snare polypectomy (HSP).DesignA prospective, multicentre, randomised controlled, parallel, non-inferiority trial conducted in 12 Japanese endoscopy units. Endoscopically diagnosed sessile adenomatous polyps, 4–9 mm in size, were randomly assigned to the CSP or HSP group. After complete removal of the polyp using the allocated technique, biopsy specimens from the resection margin after polypectomy were obtained. The primary endpoint was the complete resection rate, defined as no evidence of adenomatous tissue in the biopsied specimens, among all pathologically confirmed adenomatous polyps.ResultsA total of 796 eligible polyps were detected in 538 of 912 patients screened for eligibility between September 2015 and August 2016. The complete resection rate for CSP was 98.2% compared with 97.4% for HSP. The non-inferiority of CSP for complete resection compared with HSP was confirmed by the +0.8% (90% CI −1.0 to 2.7) complete resection rate (non-inferiority p&lt;0.0001). Postoperative bleeding requiring endoscopic haemostasis occurred only in the HSP group (0.5%, 2 of 402 polyps).ConclusionsThe complete resection rate for CSP is not inferior to that for HSP. CSP can be one of the standard techniques for 4–9 mm colorectal polyps. (Study registration: UMIN000018328)</abstract><cop>England</cop><pub>BMJ Publishing Group Ltd and British Society of Gastroenterology</pub><pmid>28970290</pmid><doi>10.1136/gutjnl-2017-314215</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-1155-3116</orcidid><orcidid>https://orcid.org/0000-0002-6826-9829</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0017-5749
ispartof Gut, 2018-11, Vol.67 (11), p.1950-1957
issn 0017-5749
1468-3288
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_6176523
source PubMed Central
subjects Biopsy
Classification
Clinical medicine
Cold
Colon
colonic polyps
Colonoscopy
Colorectal cancer
colorectal neoplasm
Endoscopy
Gastroenterology
Generalized linear models
Polyps
Tumors
title A comparison of the resection rate for cold and hot snare polypectomy for 4–9 mm colorectal polyps: a multicentre randomised controlled trial (CRESCENT study)
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T19%3A45%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20comparison%20of%20the%20resection%20rate%20for%20cold%20and%20hot%20snare%20polypectomy%20for%204%E2%80%939%20mm%20colorectal%20polyps:%20a%20multicentre%20randomised%20controlled%20trial%20(CRESCENT%20study)&rft.jtitle=Gut&rft.au=Kawamura,%20Takuji&rft.date=2018-11-01&rft.volume=67&rft.issue=11&rft.spage=1950&rft.epage=1957&rft.pages=1950-1957&rft.issn=0017-5749&rft.eissn=1468-3288&rft_id=info:doi/10.1136/gutjnl-2017-314215&rft_dat=%3Cproquest_pubme%3E2117303896%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2117303896&rft_id=info:pmid/28970290&rfr_iscdi=true