Translation acrobatics: how cancer cells exploit alternate modes of translational initiation

Recent work has brought to light many different mechanisms of translation initiation that function in cells in parallel to canonical cap‐dependent initiation. This has important implications for cancer. Canonical cap‐dependent translation initiation is inhibited by many stresses such as hypoxia, nut...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	EMBO reports 2018-10, Vol.19 (10), p.n/a
Hauptverfasser:	Sriram, Ashwin, Bohlen, Jonathan, Teleman, Aurelio A
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer Cell Hypoxia - genetics DNA Damage - genetics EMBO03 EMBO32 Genotoxicity Humans Hypoxia Mutation N6-methyladenosine Neoplasms - genetics Protein Biosynthesis Protein synthesis Proteins Proteomics Regulatory sequences Review Reviews Ribosomes - genetics stress Stresses Translation Translation initiation
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!