Genome mining, isolation, chemical synthesis and biological evaluation of a novel lanthipeptide, tikitericin, from the extremophilic microorganism Thermogemmatispora strain T81† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc02170h

Tikitericin, a novel lanthipeptide was isolated and characterised together with its first total synthesis. Genome mining of the New Zealand extremophilic microorganism Thermogemmatispora strain T81 indicated the presence of biosynthetic machinery to produce several different peptidic natural product...

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Veröffentlicht in:Chemical science (Cambridge) 2018-08, Vol.9 (37), p.7311-7317
Hauptverfasser: Xu, Buzhe, Aitken, Emma J., Baker, Benjamin P., Turner, Claire A., Harvey, Joanne E., Stott, Matthew B., Power, Jean F., Harris, Paul W. R., Keyzers, Robert A., Brimble, Margaret A.
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Sprache:eng
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