Mesenchymal Stromal Stem Cell-Derived Microvesicles Enhance Tumor Lysate Pulsed Dendritic Cell Stimulated Autologous T lymphocyte Cytotoxicity

Background: Immunotherapy is one promising therapeutic strategy against glioma, an aggressive form of brain cancer. Previous studies have demonstrated that multiple tumor antigens exist and can be used to induce tumor specific T cell responses. Furthermore, recently it was shown that TLR4-primed mes...

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Veröffentlicht in:	Asian Pacific journal of cancer prevention : APJCP 2018-07, Vol.19 (7), p.1895-1902
Hauptverfasser:	Rahmani Kukia, Nasim, Alipanah-Moghadam, Reza, Delirezh, Nowruz, Mazani, Mohammad
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, Neoplasm - immunology Cancer Vaccines - immunology Coculture Techniques Cytotoxicity, Immunologic - immunology Dendritic Cells - immunology Glioma - immunology Glioma - therapy Immunotherapy Lymphocyte Activation Mesenchymal Stromal Cells - immunology Rats Rats, Wistar T-Lymphocytes, Cytotoxic - immunology Tumor Cells, Cultured
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