Melanotic schwannoma of spine: Illustration of two cases with diverse clinical presentation and outcome
Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behav...
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Veröffentlicht in: | Asian journal of neurosurgery 2018-07, Vol.13 (3), p.881-884 |
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creator | Chandran, Raj Patil, Anil Prabhakar, Rajmohan Balachandran, Krishna |
description | Melanotic schwannomas (MS) are rare variants of schwannomas the occurrence of which is described in case reports only. They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done. |
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They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done.</description><identifier>ISSN: 1793-5482</identifier><identifier>EISSN: 2248-9614</identifier><identifier>DOI: 10.4103/ajns.AJNS_353_16</identifier><identifier>PMID: 30283573</identifier><language>eng</language><publisher>A-12, 2nd Floor, Sector 2, Noida-201301 UP, India: Thieme Medical and Scientific Publishers Pvt. 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They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done.</description><subject>Case Report</subject><subject>Melanoma</subject><subject>Prognosis</subject><subject>Spine</subject><issn>1793-5482</issn><issn>2248-9614</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>0U6</sourceid><recordid>eNp1ks9v2yAUx61p0xp1ve80IU3azSkYiPEOk9JqPzp122HbGWHyHJNiiADX2n8_Iq9VIq1wQHp8vl893peieE3wkhFML9XOxeX66_efknIqyepZsagqJspmRdjzYkHqhpacieqsuIhxh_PihHNcvSzOKK4E5TVdFNtvYJXzyWgUdT8p5_ygkO9Q3BsH79GNtWNMQSXj3aGcJo-0ihDRZFKPNuYeQgSkrXFGK4v2ASK4NPPKbZAfk_YDvCpedMpGuPh3nhe_P338df2lvP3x-eZ6fVtqhrkp1arTTcNbAgJjSgSABqo7zHTbqrqrFO44pYSJhjIOrRCkroXgjHei3kDV0vPiw-y7H9sBNjr3EpSV-2AGFf5Ir4w8vXGml1t_L1eEN7ih2eDtbLBVFqRxnc-YHkzUcs1ZgwVpMMvU8j9U3hsYjPYOOpPrJ4J3R4IelE199HY8zCmegngGdfAxBugeeydYHnKXh9zlUe5Z8ub4zY-Ch5QzcDUDk7cp53VnxwmCzOyd89OTxjKPVz78j2xyOZuk3sAAcufH4HKUT_f1F5Ty0hM</recordid><startdate>20180701</startdate><enddate>20180701</enddate><creator>Chandran, Raj</creator><creator>Patil, Anil</creator><creator>Prabhakar, Rajmohan</creator><creator>Balachandran, Krishna</creator><general>Thieme Medical and Scientific Publishers Pvt. 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They usually arise from posterior spinal nerve roots and less commonly from other cells of neural crest origin. Although they are relatively benign tumors in young, aggressive behavior is reported. They occur as isolated tumors or as part of a syndrome named Carney complex. We try to describe the pathology, diagnosis, management, and prognosis of MSs in two different cases: one cervical intramedullary with no recurrence on 5-year follow-up and the other one extramedullary in lumbar region with early recurrence and aggressive course. A brief review of literature is done.</abstract><cop>A-12, 2nd Floor, Sector 2, Noida-201301 UP, India</cop><pub>Thieme Medical and Scientific Publishers Pvt. Ltd</pub><pmid>30283573</pmid><doi>10.4103/ajns.AJNS_353_16</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Case Report Melanoma Prognosis Spine |
title | Melanotic schwannoma of spine: Illustration of two cases with diverse clinical presentation and outcome |
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