Klotho protein in neurodegenerative disorders

The Klotho protein is a recently discovered protein and its overexpression is associated with life extension. Klotho deficiency or silencing of the Klotho gene in mice leads to an accelerated aging and short life, whereas overexpression of Klotho in mice extends lifespan. Klotho participates in many...

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Veröffentlicht in:	Neurological sciences 2018-10, Vol.39 (10), p.1677-1682
Hauptverfasser:	Torbus-Paluszczak, Magdalena, Bartman, Wojciech, Adamczyk-Sowa, Monika
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Calcium metabolism Calcium phosphates Choroid plexus Cognitive ability Kidneys Klotho protein Life span Literature reviews Medicine Medicine & Public Health Metabolic pathways Multiple sclerosis Myelination Neurodegenerative diseases Neurology Neuroprotection Neuroradiology Neurosciences Neurosurgery Proteins Psychiatry Review Review Article Therapeutic applications
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